Cigarette smoke significantly reduces proliferation and modulates the expression levels of CEBPα and CEBPβ in cultured human lung fibroblasts

N. Miglino, M. Roth, M. Tamm, P. Borger (Basel, Switzerland; Sydney, Australia)

Source: Annual Congress 2008 - Basic science in asthma and COPD II
Session: Basic science in asthma and COPD II
Session type: Thematic Poster Session
Number: 1973
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. Miglino, M. Roth, M. Tamm, P. Borger (Basel, Switzerland; Sydney, Australia). Cigarette smoke significantly reduces proliferation and modulates the expression levels of CEBPα and CEBPβ in cultured human lung fibroblasts. Eur Respir J 2008; 32: Suppl. 52, 1973

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Cigarette smoke down-regulates the expression of β-catenin in primary human lung fibroblasts
Source: Annual Congress 2011 - Lung cell biology
Year: 2011

Cigarette smoke extract (CSE) induces clusterin expression in human lung fibroblasts
Source: Eur Respir J 2004; 24: Suppl. 48, 105s
Year: 2004

Cigarette smoke upregulating the expression of miR 21 increases IL-8 in airway epithelial cells
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018



Cigarette smoke decreases E-Cadherin expression downregulating FoxO3 in lung epithelial cells
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD
Year: 2019

Repeated exposure to cigarette smoke extract (CSE) in primary human lung fibroblasts – effects on proliferation rate
Source: Eur Respir J 2006; 28: Suppl. 50, 635s
Year: 2006

Cigarette smoke exposure decreases CFLAR expression in bronchial epithelium, augmenting susceptibility for cell death and DAMP release
Source: International Congress 2018 – Regenerative and anti-fibrotic approaches
Year: 2018



Cigarette smoke increases TLR4 expression and modifies LPS mediated responses in airway epithelial cells
Source: Annual Congress 2007 - Epithelial networks in the airways
Year: 2007


Increased STIM1 expression induced by cigarette smoking extracts regulates the proliferation and production of inflammatory cytokines in human airway smooth muscle cells
Source: Virtual Congress 2020 – Effects of environmental exposures on lung pathology
Year: 2020

Cigarette smoke and TGF-β1 increase p21waf1/cip1 expression in alveolar epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 97s
Year: 2002

Z-Alpha-1-antitrypsin and cigarette smoke extract impair apoptosis in human bronchial epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 797s
Year: 2006

Comparison of the gene expression profile in lung fibroblasts from patients with emphysema and changes in gene expression induced by cigarette smoke extract (CSE)
Source: Eur Respir J 2006; 28: Suppl. 50, 585s
Year: 2006

Cigarette smoke markedly inhibits the LPS-induced production of interleukin-8 in bronchial epithelial cells and consequent neutrophil migration in vitro
Source: Eur Respir J 2004; 24: Suppl. 48, 100s
Year: 2004

Carbocysteine restores the expression and the activation of TLR4 altered by cigarette smoke extracts in bronchial epithelial cells
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

Cigarette smoke impairs Sirt1 activity and promotes pro-inflammatory responses in bronchial epithelial cells
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

Effect of cigarette smoke extract or TGF-β1 on hyaluronan production and hyaluronan modulating enzymes in primary murine lung fibroblasts
Source: Annual Congress 2011 - Lung cell biology
Year: 2011


Cigarette smoke extract induces barrier changes and senescence in primary bronchial epithelial cells
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

Cigarette smoke exposure disrupts the molecular regulation of mitochondrial metabolism in human bronchial and alveolar epithelial cells
Source: ERS Lung Science Conference 2020
Year: 2020

Cigarette smoke extract and diesel particles result in the production of pro-inflammatory molecules from human primary lung fibroblast strains and pulmonary epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 413s
Year: 2001

Downregulation of lysosome-associated membrane protein-2A accelerates cigarette smoke extract-induced aging and apoptosis in human bronchial epithelial cells
Source: International Congress 2019 – Cellular responses and cell therapy in lung injury and repair
Year: 2019

Cigarette smoke induces mitochondrial dysfunction via PKCd-p66Shc signaling pathway in human bronchial epithelial cells
Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium
Year: 2018