Counteracting the ET-1 induced pathological cell proliferation by bosentan – nuclear expression of cell cycle inhibitors p21 (waf1) and p27 (kip1) induces G1-arrest in pulmonary artery smooth muscle cells

C. Lambers, P. Binder, M. Will, E. Hofbauer, M. Roth, V. Petkov, L. H. Block (Vienna, Austria; Sydney, Australia)

Source: Annual Congress 2008 - Pulmonary vascular biology
Session: Pulmonary vascular biology
Session type: Thematic Poster Session
Number: 987
Disease area: Pulmonary vascular diseases

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C. Lambers, P. Binder, M. Will, E. Hofbauer, M. Roth, V. Petkov, L. H. Block (Vienna, Austria; Sydney, Australia). Counteracting the ET-1 induced pathological cell proliferation by bosentan – nuclear expression of cell cycle inhibitors p21 (waf1) and p27 (kip1) induces G1-arrest in pulmonary artery smooth muscle cells. Eur Respir J 2008; 32: Suppl. 52, 987

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