Expression of angiogenic growth factors and stromal cell derived factor-1/CXC chemokine receptor 4 (SDF-1/CXCL12 – CXCR4) biological axis in idiopathic pulmonary fibrosis: a lung tissue study

A. Proklou, K. Antoniou, G. Soufla, F. Economidou, K. Samara, M. Manousakis, I. Drositis, D. Spandidos, N. Siafakas (Heraklion, Greece)

Source: Annual Congress 2008 - New insights into the pathogenesis of idiopathic pulmonary fibrosis and sarcoidosis
Disease area: Interstitial lung diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Proklou, K. Antoniou, G. Soufla, F. Economidou, K. Samara, M. Manousakis, I. Drositis, D. Spandidos, N. Siafakas (Heraklion, Greece). Expression of angiogenic growth factors and stromal cell derived factor-1/CXC chemokine receptor 4 (SDF-1/CXCL12 – CXCR4) biological axis in idiopathic pulmonary fibrosis: a lung tissue study. Eur Respir J 2008; 32: Suppl. 52, 196

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Differential expression of stromal cell derived factor-1/CXC chemokine receptor 4 (SDF-1/CXCL12 – CXCR4) biological axis between idiopathic pulmonary fibrosis and interstitial pneumonia associated with collagen vascular disease: a bronchoalveolar la
Source: Annual Congress 2008 - Interstitial lung disease in systemic and vascular disorders
Year: 2008

Increased expression of angiogenic growth factor stromal cell derived factor-1 (SDF-1/CXCL12) in pleural fluid of patients with lung cancer: preliminary results
Source: Annual Congress 2008 - Biology and prognosis in thoracic oncology
Year: 2008

Down regulation of stromal cell-derived factor 1 (SDF-1/CXCL12) in lung tissue of patients with idiopathic pulmonary fibrosis
Source: Eur Respir J 2007; 30: Suppl. 51, 574s
Year: 2007

Contribution of genetic polymorphism of stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, to the susceptibility and severity of non-small cell lung cancer
Source: Annual Congress 2010 - Biomarkers for lung cancer
Year: 2010

Wnt11 inhibits effects of transforming growth factor-beta1 (TGFbeta1) on lung epithelial phenotype
Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation
Year: 2013


A role for the CXCL12 receptor, CXCR7, in the pathogenesis of human pulmonary vascular disease
Source: Eur Respir J 2012; 39: 1415-1424
Year: 2012



Elevated integrin ?5 expression in idiopathic pulmonary fibrosis (IPF) derived fibroblasts is linked to paracrine TNF-a signaling
Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis
Year: 2017

Idiopathic pulmonary fibrosis fibroblasts migrate and proliferate to CC chemokine ligand 21
Source: Eur Respir J 2007; 29: 1082-1093
Year: 2007



Expression of vascular endothelial growth factor (VEGF) and its receptors (VEFG-R1-Flt1, VEGF-R2-Flk1) in non small cell lung carcinomas (NSCLC): correlation with lymphangiogenesis and clinical outcome
Source: Annual Congress 2007 - Diagnosis and prognosis in thoracic oncology
Year: 2007


T-helper cell type-1 transcription factor T-bet is upregulated in pulmonary sarcoidosis
Source: Eur Respir J 2011; 38: 1136-1144
Year: 2011



Production of a novel isoform of vascular endothelial growth factor (VEGF) by the normal human lung
Source: Eur Respir J 2006; 28: Suppl. 50, 822s
Year: 2006

Haemophilus influenzae (NTHi) up-regulates acute inflammation in human lung tissue and causes downregulation of transforming growth factor-beta (TGF-beta) – A possible role of NTHi in remodeling processes in human lung tissue
Source: Annual Congress 2010 - Novel cellular mechanisms in lung disease
Year: 2010

Epidermal growth factor receptor (EGFR) activation is required for TGFbeta1-induced epithelial-mesenchymal transition (EMT) in idiopathic pulmonary fibrosis (IPF)
Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation
Year: 2013

Chemokine receptor expression by human lung mast cells
Source: Annual Congress 2003 - Cell signalling and cytokines in asthma
Year: 2003


Overexpression of B cell activating factor (BAFF) in peripheral lung of COPD patients
Source: Annual Congress 2009 - Pathology and immunology of COPD
Year: 2009


Fibroblast growth factor 9 (FGF9) modulates mesothelial cells plasticity to decrease differentiation and migration in vitro
Source: International Congress 2016 – Common mechanisms in lung development and fibrosis
Year: 2016

Morphometric study of hypoxia inducible factor-1α-vascular endothelial growth factor (HIF-1α-VEGF) axis in patients with idiopathic pulmonary fibrosis with the use of tissue microarrays
Source: Eur Respir J 2006; 28: Suppl. 50, 338s
Year: 2006

The influence of sera from interstitial lung diseases (ILD) patients on human mononuclear cells (MNC) production of vascular endothelial growth factor (VEGF)
Source: Eur Respir J 2004; 24: Suppl. 48, 553s
Year: 2004

Increased vascular endothelial growth factor (VEGF) secretion from activated T cells in COPD
Source: Annual Congress 2007 - Cell-based tissue modulation: the good and the ugly?
Year: 2007


Increased immunoreactivity of stromal cell-derived factor-1 and angiogenesis in asthma
Source: Eur Respir J 2003; 21: 804-809
Year: 2003