Role of thrombin and thrombin receptor in the activation of human bronchial epithelial cells during airway inflammation

M. Profita, A. Bonanno, F. Pompeo, L. Siena, M. Ferraro, A. M. Montalbano, L. Riccobono, R. Gagliardo, G. Bonsignore, M. Gjomarkaj (Palermo, Italy)

Source: Annual Congress 2007 - The best of airway epithelial cells
Session: The best of airway epithelial cells
Session type: Oral Presentation
Number: 3154
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Profita, A. Bonanno, F. Pompeo, L. Siena, M. Ferraro, A. M. Montalbano, L. Riccobono, R. Gagliardo, G. Bonsignore, M. Gjomarkaj (Palermo, Italy). Role of thrombin and thrombin receptor in the activation of human bronchial epithelial cells during airway inflammation. Eur Respir J 2007; 30: Suppl. 51, 3154

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Thrombin stimulates mucin secretion from airway epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 570s
Year: 2002

Modulation of neutrophil activation and survival by bronchial epithelial cells
Source: Eur Respir J 2004; 24: Suppl. 48, 437s
Year: 2004

Activation of PAR-2 enhances ICAM-1 expression and IL-8 release in airway epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 571s
Year: 2002

Rhinovirus-induced proinflammatory cascade in bronchial epithelial cells requires xanthine-oxidase system activation
Source: Annual Congress 2008 - New diagnostic methods in viral and atypical infections
Year: 2008


Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells
Source: Eur Respir J 2012; 39: 439-445
Year: 2012



Effects of protease-activated receptor-2 stimulation on human and rodent airway mucus secretion
Source: Eur Respir J 2002; 20: Suppl. 38, 573s
Year: 2002

Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells
Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies
Year: 2020


Induction of proteinase-activated receptor-2 (PAR-2) expression by IL-1β and tryptase in human airway smooth muscle cells in culture
Source: Eur Respir J 2002; 20: Suppl. 38, 170s
Year: 2002

CysLT1 receptor activation-induced adhesion of human eosinophils to bronchial epithelial cells: signal transduction and pharmacological modulation
Source: Eur Respir J 2005; 26: Suppl. 49, 368s
Year: 2005

Increased extracellular pressure stimulates interleukin-8 secretion by human bronchial epithelial cells
Source: Annual Congress 2010 - Lung cell biology and immunology
Year: 2010

Effect of activated protein C on the thrombin signalling pathway in alveolar epithelial cells
Source: Annual Congress 2009 - Acute lung injury: biological mechanisms
Year: 2009

Effect of chronic stimulation of protease activating receptor-2 in human bronchial smooth muscle cells
Source: Annual Congress 2010 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2010

Activation of bone morphogenetic protein(BMP)/Smad signaling in bronchial epithelial cells during airway inflammation
Source: Eur Respir J 2002; 20: Suppl. 38, 372s
Year: 2002

Role of purinergic receptors in the activation of human airway smooth muscle cells by the antimicrobial peptide LL-37
Source: Eur Respir J 2006; 28: Suppl. 50, 339s
Year: 2006

Human bronchial epithelium expresses interleukin-9 receptor and releases neutrophil chemotactic factor
Source: Eur Respir J 2001; 18: Suppl. 33, 19s
Year: 2001

Role of purinergic receptors in the activation of human airway smooth muscle cells by the antimicrobial peptide LL-37
Source: Eur Respir Rev 2006; 15: 182-184
Year: 2006



CD40 ligation modulates inflammatory cytokines production by human bronchial epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 246s
Year: 2001

Interactions between zinc deficiency and murine airway inflammation on apoptosis in airway epithelium
Source: Eur Respir J 2003; 22: Suppl. 45, 267s
Year: 2003

Interaction of macrophages and airway epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 590s
Year: 2006