Characterisation of guinea pig precision-cut lung slices: comparison with human tissues

Ressmeyer A. R., Larsson A. K., Vollmer E., Dahlen S. E., Uhlig S., Martin C.

Source: Eur Respir J 2006; 28: 603-611
Journal Issue: September
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Ressmeyer A. R., Larsson A. K., Vollmer E., Dahlen S. E., Uhlig S., Martin C.. Characterisation of guinea pig precision-cut lung slices: comparison with human tissues. Eur Respir J 2006; 28: 603-611

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Comparison of distal lung innervation in human and guinea pig precision-cut lung slices (PCLS)
Source: Annual Congress 2011 - Cell biology of lung disease
Year: 2011

Studying human airway pharmacology in microsections: application of videomicrometry
Source: Eur Respir J 2002; 19: 991-996
Year: 2002



Intercellular communication between epithelial and smooth muscle cells of airways in mouse lung slices
Source: Annual Congress 2006 - Airway epithelial cells in inflammation
Year: 2006


Relaxin potentiates ß2-adrenoceptor mediated bronchodilation in precision-cut lung slices (PCLS) from mouse models of airway inflammation and fibrosis, and in human airways
Source: International Congress 2019 – Advances in asthma pharmacology
Year: 2019

Small airway reactivity is not altered in precision-cut lung slices from a bleomycin mouse model of airway fibrosis
Source: International Congress 2018 – Basic pharmacology
Year: 2018

The effects of PGD2 and DK-PGD2 on features of airway remodeling in human airway epithelial cells and guinea pig lung slices
Source: Virtual Congress 2020 – Clinical and laboratory pharmacology in asthma
Year: 2020


The mediators of allergen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung (IPL) are closely similar to those in asthmatics
Source: Eur Respir J 2003; 22: Suppl. 45, 104s
Year: 2003

Mechanism of NK1-mediated bronchoconstriction in passively sensitized human lung tissue.
Source: International Congress 2018 – Translational models of the immunopathology that underlies airway obstructive diseases
Year: 2018

PP214 – Human precision-cut lung slices generated from excess donor lungs as a model for IPF and drug screening
Source: ERS Lung Science Conference 2021
Year: 2021

LSC 2010 Abstract: Experimental asthma: expression and activation of protein kinase C isoenzymes in airway smooth muscles (ASM) & lymphocytes and structural changes in lung tissues during the development of airway hypersensitivity in guinea pig model of asthma
Source: Annual Congress 2010 - COPD and asthma: models and human studies
Year: 2010

ENaC-activating effect of AP301 in type II alveolar cells isolated from dog, pig and rat lungs
Source: Annual Congress 2012 - The best of pharmacology treatment for asthma and COPD
Year: 2012

Effects of allergen on airway narrowing dynamics as assessed by lung-slice technique
Source: Eur Respir J 2008; 31: 532-538
Year: 2008



Embryonic and adult stem cells: potential for regenerating the epithelium of the lung
Source: Annual Congress 2007 - WS1 - Educational Workshop: epithelial cell biology: culture methods and functional studies
Year: 2007


Effect of luminal osmolarity on ion content of connective tissue in rat trachea after epithelial damage
Source: Eur Respir J 2001; 18: 810-816
Year: 2001



Different patterns of mast cell activation and smooth muscle contractions by MRGPRX2 agonist and antigen in guinea pig trachea
Source: Virtual Congress 2020 – New insight into the pathogenesis of chronic lung diseases: asthma, COPD and others
Year: 2020


Effects of neurokinins on nNOS expression in bronchial epithelial and inflammatory cells in airways of guinea pigs
Source: Eur Respir J 2005; 26: Suppl. 49, 340s
Year: 2005

Kinetics of in vitro bronchoconstriction in an elastolytic mouse model of emphysema
Source: Eur Respir J 2007; 30: 691-700
Year: 2007



Induction of pro-fibrotic biomarkers in precision-cut lung slices (PCLS)
Source: International Congress 2016 – IPF pathogenesis
Year: 2016

Cardiotonic agents affect pulmonary vessels in precision-cut lung slices (PCLS)
Source: Annual Congress 2011 - Treatment of pulmonary hypertension
Year: 2011

Pro-fibrotic biomarkers in ex vivo lung tissue slices: A species comparison
Source: International Congress 2017 – Lung fibrosis: basic science
Year: 2017