Source: Annual Congress 2002 - Genes and proteins in lung injury
Disease area: Pulmonary vascular diseases



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S. Krick, J. Hänze, J. Appel, A. H. Ghofrani, R. Schermuly, F. Grimminger, W. Seeger, F. Rose (Giessen, Germany). Angiotensin II and hypoxia synergistically induce proliferation in pulmonary artery fibroblasts by a PI-3K and PKC-signaling pathway through HIF-1 a and upregulation of angiotensin II-receptors type I. Eur Respir J 2002; 20: Suppl. 38, 2352

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