Montelukast inhibits bronchoconstriction and gas exchange defects induced by leukotriene D4 challenge in asthma

A. Casas, F. P. Gómez, F. Burgos, B. Dahlén, S. E. Dahlén, J. A. Barberà, J. Roca, R. Rodriguez-Roisin (Barcelona, Spain; Stockholm, Sweden)

Source: Annual Congress 2002 - Airway reactivity
Session: Airway reactivity
Session type: Thematic Poster Session
Number: 1936
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Casas, F. P. Gómez, F. Burgos, B. Dahlén, S. E. Dahlén, J. A. Barberà, J. Roca, R. Rodriguez-Roisin (Barcelona, Spain; Stockholm, Sweden). Montelukast inhibits bronchoconstriction and gas exchange defects induced by leukotriene D4 challenge in asthma. Eur Respir J 2002; 20: Suppl. 38, 1936

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Salbutamol but not ipratropium fully abolish leukotriene D4-induced gas exchange abnormalities and induced sputum eosinophilia in asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 412s
Year: 2003

The CysLT1 receptor antagonist montelukast blocks bronchoconstriction induced by inhaled leukotriene E4 in subjects with asthma
Source: International Congress 2015 – The immunology of allergic airway disease
Year: 2015

Formoterol protects against platelet-activating factor-induced effects in asthma
Source: Eur Respir J 2004; 23: 71-75
Year: 2004



The CysLT1 receptor antagonist montelukast inhibits mast cell activation induced by inhaled leukotriene E4 in subjects with asthma
Source: International Congress 2016 – Clinical and molecular studies in asthma
Year: 2016


Effect of combined leukotriene, histamine antagonism on the early response to inhaled allergen
Source: Eur Respir J 2005; 26: Suppl. 49, 583s
Year: 2005

Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in the airway remodeling induced by chronic airway inflammation in guinea pigs
Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II
Year: 2008

Dose-response of leukotriene CysLT1-receptor antagonist on nasal lysine-aspirin challenge in patients with aspirin-induced asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 585s
Year: 2004

The inhaled PDE4 inhibitor UK-500,001 does not significantly inhibit airway responses to allergen and histamine
Source: Annual Congress 2007 - New drugs for asthma
Year: 2007


Inhaled corticosteroids and leukotriene receptor antagonists induce protection against adenosine 5‘monophosphate induced bronchospasm in a synergic fashion
Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring
Year: 2007


Montelukast protects against nasal lysine-aspirin challenge in patients with aspirin-induced asthma
Source: Eur Respir J 2004; 24: 226-230
Year: 2004



Fluticasone propionate attenuates platelet-activating factor-induced gas exchange defects in mild asthma
Source: Eur Respir J 2002; 19: 872-878
Year: 2002



The effect of a leukotriene antagonist, pranlukast, on allergen-induced airway responses and circulating dendritic cells in subjects with atopic asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 414s
Year: 2003

Inhibition of the inhaled allergen challenge response by the CRTH2 antagonist OC000459 in patients with asthma
Source: Annual Congress 2010 - Novel anti-inflammatory agents for airway disease
Year: 2010

Cysteinyl leukotrienes and leukotriene B4 in expired breath condensate in patients with chronic asthma treated with montelukast
Source: Eur Respir J 2003; 22: Suppl. 45, 101s
Year: 2003

Dose reduction of inhaled corticosteroids under concomitant medication with montelukast in patients with asthma
Source: Eur Respir J 2002; 20: 1080-1087
Year: 2002



The inhaled PDE4 inhibitor GSK256066 significantly inhibits airway responses following allergen challenge in asthmatics
Source: Annual Congress 2008 - Novel treatments for respiratory disease
Year: 2008


Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication
Source: Annual Congress 2009 - Models of chronic airways disease and therapy
Year: 2009


Protective effect of cysteinyl leukotriene receptor antagonist montelukast in bleomycin induced pulmonary fibrosis
Source: Eur Respir J 2007; 30: Suppl. 51, 111s
Year: 2007

The effects of a cysteinyl leukotriene receptor antagonist, pranlukast, on dendritic cell chemoattractants in the airways of subjects with asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 132s
Year: 2004

Anti-inflammatory effects of histamine H1-receptor antagonist and leukotriene CysLT1-receptor antagonist in patients with atopic asthma maintained on inhaled corticosteroids
Source: Eur Respir J 2004; 24: Suppl. 48, 221s
Year: 2004