Polymorphism in C-C Chemokine Receptor 5 (CCR5) increases susceptibility to Löfgren’s syndrome and alters receptor expression as well as functional response.

B. Karakaya (Nieuwegein, Netherlands), C. Van Moorsel (Nieuwegein, Netherlands), M. Veltkamp (Nieuwegein, Netherlands), C. Benschop (Nieuwegein, Netherlands), K. Kazemier (Utrecht, Netherlands), A. Van Der Helm-Van Mil (Leiden, Netherlands), T. Huizinga (Leiden, Netherlands), J. Grutters (Nieuwegein, Netherlands), G. Rijkers (Middelburg, Netherlands)

Source: Virtual Congress 2021 – Better understanding of sarcoidosis: new keys
Session: Better understanding of sarcoidosis: new keys
Session type: Oral Presentation
Number: 3980

Congress or journal article abstractWebcastSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
B. Karakaya (Nieuwegein, Netherlands), C. Van Moorsel (Nieuwegein, Netherlands), M. Veltkamp (Nieuwegein, Netherlands), C. Benschop (Nieuwegein, Netherlands), K. Kazemier (Utrecht, Netherlands), A. Van Der Helm-Van Mil (Leiden, Netherlands), T. Huizinga (Leiden, Netherlands), J. Grutters (Nieuwegein, Netherlands), G. Rijkers (Middelburg, Netherlands). Polymorphism in C-C Chemokine Receptor 5 (CCR5) increases susceptibility to Löfgren’s syndrome and alters receptor expression as well as functional response.. 3980

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
C-C chemokine receptor 2 gene polymorphism V64I and C-C chemokine receptor 5 gene polymorphism Δ32 in pulmonary sarcoidosis patients
Source: Eur Respir J 2006; 28: Suppl. 50, 520s
Year: 2006

LSC Abstract – Toll-like receptor 10: Expression and functional role in LPS mediated inflammation
Source: International Congress 2015 – Respiratory translational research: novel mechanisms, diagnostic markers and Space Odyssey
Year: 2015

Polymorphism of chemokine receptor gene CCR5 in patients with lung cancer
Source: Eur Respir J 2003; 22: Suppl. 45, 266s
Year: 2003

C-C chemokine receptor 2 gene polymorphism V64I and CCR2 expression on T lymphocytes in pulmonary sarcoidosis patients
Source: Eur Respir J 2005; 26: Suppl. 49, 268s
Year: 2005

Sepsis and endotoxaemia differentially modulate Toll-like receptor 2, 4 and CD14 expression on human monocytes
Source: Eur Respir J 2005; 26: Suppl. 49, 222s
Year: 2005

Increased expression of toll-like receptor 2 (TLR2) in the small airways of fatal asthma
Source: Eur Respir J 2007; 30: Suppl. 51, 285s
Year: 2007

CC chemokine receptor 5 gene polymorphisms in beryllium disease
Source: Eur Respir J 2010; 36: 331
Year: 2010



Deletion in macrophage chemokine receptor gene (CCR5) in children with bronchial asthma (BA)
Source: Eur Respir J 2001; 18: Suppl. 33, 450s
Year: 2001

A small-molecule compound targeting CCR5 and CXCR3 prevents airway hyperresponsiveness and inflammation
Source: Eur Respir J 2008; 31: 783-789
Year: 2008



Does high amplitude mechanical stretch influence toll like receptor 4 (TLR4) expression and signaling?
Source: Annual Congress 2010 - Determinants of acute lung injury and fibrosis
Year: 2010

CARD15/NOD2, CD14, and toll-like receptor 4 gene polymorphisms in Greek patients with sarcoidosis
Source: Eur Respir J 2006; 28: Suppl. 50, 520s
Year: 2006

IL33 receptor activation is IL33 isoform and receptor genotype specific
Source: International Congress 2019 – Crosstalk in chronic pulmonary diseases
Year: 2019

Elevated CCL2 responses in COPD and attenuation by selective chemokine receptor antagonists
Source: International Congress 2015 – Therapeutic approaches in inflammatory lung disease
Year: 2015

Influence of Toll-like receptor 4 (TLR4) on cellular signaling of acute lung injury
Source: Eur Respir J 2003; 22: Suppl. 45, 268s
Year: 2003

Cigarette smoke up-regulates toll like receptor 4 (TLR4) expression and enhances TLR4 mediated responses
Source: Eur Respir J 2005; 26: Suppl. 49, 555s
Year: 2005

The Arg753Gln polymorphism of the human Toll-like receptor 2 gene in tuberculosis disease
Source: Eur Respir J 2004; 23: 219-223
Year: 2004



Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk
Source: Annual Congress 2008 - Risk factors for allergic asthma and allergic rhinitis
Year: 2008


Polymorphisms in CCR5 confer susceptibility to Löfgren‘s syndrome and may regulate the immune response
Source: Annual Congress 2011 - Biomarkers in sarcoidosis
Year: 2011

Polarization of the chemokine receptor CXCR6 according to activation status of human lung T cells
Source: Eur Respir J 2003; 22: Suppl. 45, 571s
Year: 2003

Differential expression and regulation of toll-like receptors 1-9 in human airway epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 19s
Year: 2001