Senescent human bronchial epithelial cells induce small airway fibrosis in mice

N. Saito (Barcelona, Spain), F. Hernandez (Barcelona, Spain), F. Pietrocola (Barcelona, Spain), M. Serrano (Barcelona, Spain)

Source: Virtual Congress 2021 – Emerging new mechanisms of chronic lung disease
Session: Emerging new mechanisms of chronic lung disease
Session type: E-poster
Number: 863

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. Saito (Barcelona, Spain), F. Hernandez (Barcelona, Spain), F. Pietrocola (Barcelona, Spain), M. Serrano (Barcelona, Spain). Senescent human bronchial epithelial cells induce small airway fibrosis in mice. 863

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
TGFβ does not induce myofibroblast phenotype in primary human bronchial epithelial cells
Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation
Year: 2009


Co-culture of human airway epithelial cells alter the proliferation of human airway smooth muscle cells
Source: Eur Respir J 2002; 20: Suppl. 38, 572s
Year: 2002

PBI-4050 reduces expression of fibrosis biomarkers in the BioMAP SAEMyoF primary human small airway epithelial cells and lung myofibroblasts system
Source: International Congress 2017 – Systemic and airway biomarkers
Year: 2017


Human small airway epithelial cells express MMP12
Source: Eur Respir J 2007; 30: Suppl. 51, 144s
Year: 2007

Interaction of macrophages and airway epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 590s
Year: 2006

Primary bronchial epithelial cells from stable lung allografts induce the differentiation of monocytes into macrophage like cells
Source: Annual Congress 2008 - New insights and treatment options for bronchiolitis obliterans syndrome after lung transplantation
Year: 2008

Identification of MSC-like cells in human lung parenchyma capable of differentiating into airway epithelial cells
Source: Annual Congress 2009 - From emphysema to fibrosis: mechanisms of cellular remodelling in the diseased lung
Year: 2009

Do characteristic airway epithelial change precede the development of lung fibrosis? Ectopic epithelial marker protein expression in bleomycin induced fibrosis replicates that seen in bronchiolized epithelium in IPF
Source: Annual Congress 2012 - Cell culture and animal models of lung disease
Year: 2012

Investigation of the CFTR-TGFß1 interaction in inflammatory and fibrotic processes in healthy and CFTR-mutated human bronchial epithelial cells
Source: International Congress 2019 – Infection and inflammation in cystic fibrosis
Year: 2019

TLR-4 expression is reduced in cystic fibrosis bronchial epithelial cells
Source: Annual Congress 2008 - Cystic fibrosis: novel aspects of airway function and inflammation
Year: 2008



Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells
Source: Eur Respir J 2012; 39: 439-445
Year: 2012



Inhibition of CFTR-specific miRNAs in CF bronchial epithelial cells
Source: International Congress 2017 – Therapeutic approaches in lung disease
Year: 2017


ST2 on airway bronchial epithelial cell promotes vascular remodelling in the lung
Source: Annual Congress 2010 - Epithelial cells: cell biology and role in lung disease
Year: 2010

Primary human airway epithelial cells inhibit proliferation of lung fibroblasts via transforming growth factor-β
Source: Annual Congress 2007 - Acute and chronic lung injury and its repair: novel molecular insight
Year: 2007


Engineered nanoparticles induce apoptosis of human bronchial epithelial cells
Source: Annual Congress 2011 - Lung cell biology
Year: 2011

Comparison of nasal and bronchial epithelial cell inflammatory phenotype
Source: Eur Respir J 2006; 28: Suppl. 50, 235s
Year: 2006