Detection of aberrant methylation of p16(INK4a) and MGMT in endobronchial specimens increases the diagnostic yield in cases of suspected peripheral lung carcinomas

P. Litterst, L. Freitag, B. Obertrifter (Hemer, Germany)

Source: Annual Congress 2002 - Thoracic oncology: biology
Session: Thoracic oncology: biology
Session type: Oral Presentation
Number: 137
Disease area: Thoracic oncology

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
P. Litterst, L. Freitag, B. Obertrifter (Hemer, Germany). Detection of aberrant methylation of p16(INK4a) and MGMT in endobronchial specimens increases the diagnostic yield in cases of suspected peripheral lung carcinomas. Eur Respir J 2002; 20: Suppl. 38, 137

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Aberrant methylation in lung cancer identified by EBUS-TBNA as a marker of advanced staging
Source: Annual Congress 2012 - Progress in endoscopy for lung cancer
Year: 2012

Recognition of aberrant promoter methylation for early diagnosis of lung cancer patients
Source: Virtual Congress 2020 – Screening and early lung cancer
Year: 2020

Loss of heterozygosity off the P16, P53 and APC gene in oral cavity exfoliate cytologic material among lung cancer patients
Source: Eur Respir J 2005; 26: Suppl. 49, 457s
Year: 2005

Correlation of P53 and CerbB-2 expression in the diagnostic biopsies and the corresponding resected tumors in non small cell lung caner
Source: Eur Respir J 2004; 24: Suppl. 48, 43s
Year: 2004

Aberrant promoter methylation in sputum and bronchial washing in patients at risk for lung cancer
Source: Annual Congress 2009 - Genetics in the smokers corner: from inflammation in smokers via COPD to cancer
Year: 2009


Hypermethylation pattern in genomic DNA samples derived from tumor and serum of resected non-small cell lung cancer patients
Source: Eur Respir J 2004; 24: Suppl. 48, 674s
Year: 2004

Aberrant promoter methylation of CDH13 and MGMT genes is associated with clinicopathological characteristics of primary non small cell lung carcinoma
Source: Annual Congress 2012 - New aspects of lung cancer biology
Year: 2012

Dysplasia and aberrant methylation profiles in risk and lung cancer patients
Source: Eur Respir J 2005; 26: Suppl. 49, 458s
Year: 2005

The role of P53 tumor suppressor gene mutations in early diagnosis of lung cancer among patients with solitary pulmonary nodule
Source: Annual Congress 2009 - Pathogenesis of lung cancer
Year: 2009

Expression of protein onkological marker onkoprobe in peripheral blood in cases of tracheal invasion and lung metastases of thyroid carcinoma
Source: Eur Respir J 2002; 20: Suppl. 38, 466s
Year: 2002

HER-2/neu expression in bioptic and surgical samples of non small cell lung carcinoma
Source: Eur Respir J 2002; 20: Suppl. 38, 3s
Year: 2002

Detection of k-ras mutations in cytologic specimen of lung cancer patients as predictive factor of targeted therapy
Source: Annual Congress 2010 - Biomarkers for lung cancer
Year: 2010

Shox2, a biomarker for confirming malignancy in bronchial lavage from patients with suspected lung cancer and inconclusive cytology
Source: Annual Congress 2009 - Diagnosis and treatment of lung cancer
Year: 2009


Correlation of p53, EGFR and HER2 expression in the diagnostic biopsies and the corresponding resected tumours in NSCLC
Source: Eur Respir J 2003; 22: Suppl. 45, 198s
Year: 2003

Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer
Source: Annual Congress 2012 - Progress in endoscopy for lung cancer
Year: 2012

Concordance of p53 and K-ras mutations in induced sputum and corresponding biopsies of patients with nonsmall cell lung cancer (NSCLC)
Source: Eur Respir J 2001; 18: Suppl. 33, 18s
Year: 2001

The frequency and significance of radiologically detected indeterminate pulmonary nodules in patients with colorectal cancer
Source: Annual Congress 2011 - Imaging, functional evaluation and staging for lung cancer patients
Year: 2011


EGFR and K-ras mutations in cytologic samples from fine-needle aspirates in NSCLC patients
Source: Eur Respir J 2012; 40: 267-269
Year: 2012


p16INK4a promoter hypermethylation in tissue, blood, and sputum from non-small cell lung cancer and pulmonary inflammation
Source: Eur Respir J 2006; 28: Suppl. 50, 813s
Year: 2006

Interobserver agreement in determining non-small cell lung cancer subtype in specimens acquired by EBUS-TBNA},
Source: Eur Respir J 2012; 40: 699-705
Year: 2012