Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
Toll-like receptor stimulation induces airway hyperresponsiveness to bradykinin, an effect mediated by JNK and NF-κB signaling pathways Source: Eur Respir J 2005; 26: Suppl. 49, 732s Year: 2005
TNF-α inhibits human eosinophil apoptosis by activating p55 receptor and NF-κB Source: Eur Respir J 2001; 18: Suppl. 33, 162s Year: 2001
Synergistic action of formoterol on budesonide-generated decrease of proteoglycan production by activated lung fibroblasts is mediated via β-adrenergic receptor and is dependent on glucocorticoid receptor Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
Eosinophil adhesion to cholinergic nerve cells induces NFκB activation via the interleukin-1 receptor associated kinase (IRAK) pathway and upregulates ICAM-1 expression Source: Eur Respir J 2003; 22: Suppl. 45, 10s Year: 2003
Neutrophil elastase causes MUC5AC mucin synthesis via a EGF receptor, ERK and NF-kB pathway in A549 cells Source: Eur Respir J 2004; 24: Suppl. 48, 554s Year: 2004
Bradykinin phosphorylates ERK1/2 through epidermal growth factor receptor transactivation in human lung fibroblasts Source: Eur Respir J 2005; 26: Suppl. 49, 341s Year: 2005
TGFβ overproduction in asthma reduces the epithelial repair by down-regulating the leptin/leptin receptor pathway Source: Eur Respir J 2007; 30: Suppl. 51, 59s Year: 2007
Human rhinovirus induces the expression of the membrane bound form of its cellular receptor intercellular adhesion molecule 1via a tyrosine kinase dependent signal transduction pathway Source: Eur Respir J 2001; 18: Suppl. 33, 160s Year: 2001
Pseudomonas aeruginosa induces MUC5AC production via epidermal growth factor receptor Source: Eur Respir J 2002; 20: 1263-1270 Year: 2002
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
Activation of WNT co-receptor LRP5 is required for WNT and TGF-ß1 induced fibroblast activation Source: Virtual Congress 2020 – Physiological and cellular mechanisms affecting pulmonary pathologies Year: 2020
Protease activated receptor-1 (PAR-1) stimulation leads to αvβ6 integrin mediated TGFβ activation via rho kinase Source: Eur Respir J 2005; 26: Suppl. 49, 238s Year: 2005
Activation of protease-activated receptor 2 elicits epithelial-mesenchymal transition in HBE cells via ROS signaling Source: International Congress 2017 – Therapeutic approaches in lung disease Year: 2017
The muscarinic receptors promote IL-8 release in airway epithelial cells via the pERK42/44 and NF-kB pathways Source: Eur Respir J 2006; 28: Suppl. 50, 746s Year: 2006
Increased activation of TGF beta signal transduction via Smad2/3 in the airways of mice lacking T-bet Source: Eur Respir J 2002; 20: Suppl. 38, 1s Year: 2002
A differential role for ceramide kinase in antigen/FcεRI mediated mast cell activation and function Source: Eur Respir J 2006; 28: Suppl. 50, 231s Year: 2006
Transmission of muscarinic receptor mediated proliferative effects in human lung fibroblasts involves ERK-MAP kinase, but not PI-3 kinase and Rho-kinase pathway Source: Annual Congress 2007 - Miscellaneous pulmonary pharmacology Year: 2007
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004