Inhaled antibodies: targeting tumour necrosis factor receptor 1 and thymic stromal lymphopoietin

C. Summers (Cambridge (Cambridgeshire), United Kingdom)

Source: International Congress 2019 – Inhaled medicines and biological therapies in the current era of systemic treatments
Disease area: Airway diseases

WebcastSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
C. Summers (Cambridge (Cambridgeshire), United Kingdom). Inhaled antibodies: targeting tumour necrosis factor receptor 1 and thymic stromal lymphopoietin. International Congress 2019 – Inhaled medicines and biological therapies in the current era of systemic treatments

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
IL-4Ra signaling is required for thymic stromal lymphopoietin (TSLP)-induced type 2 airway inflammation
Source: Virtual Congress 2021 – Pearls in immunology, outcome studies and clinical trials in asthma, alpha-1 antitrypsin deficiency and COPD
Year: 2021



FcepsilonRI-mediated thymic stromal lymphopoietin production by interleukin-4-primed human mast cells
Source: Eur Respir J 2009; 33: 425-435
Year: 2009



Mast cell-derived tumour necrosis factor is essential for allergic airway disease
Source: Eur Respir J 2008; 31: 773-782
Year: 2008



Increased immunoreactivity of stromal cell-derived factor-1 and angiogenesis in asthma
Source: Annual Congress 2004 - Inflammation and remodelling in human lungs
Year: 2004


Thymic stromal lymphopoietin promotes asthmatic airway remodeling in human lung fibroblast cells through stat3 signaling pathway
Source: Annual Congress 2012 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2012

Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: the role of thymic stromal lymphopoietin
Source: International Congress 2018 – Roles of innate lymphoid cells in asthma
Year: 2018


Increased immunoreactivity of stromal cell-derived factor-1 and angiogenesis in asthma
Source: Eur Respir J 2003; 21: 804-809
Year: 2003



Blockade of thymic stromal lymphopoietin receptor (TSLPR) reduces atopic inflammation in a cynomolgus monkey model of asthma
Source: Annual Congress 2012 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2012

Peripheral blood TSLP (thymic stromal lymphopoietin) in children as a biomarker?
Source: Virtual Congress 2021 – Biomarkers and risk factors in childhood asthma
Year: 2021


Vanadium pentoxide induced epithelial innate cytokines IL-25, IL-33, and thymic stromal lymphopoietin (TSLP) through activating MAPK pathway
Source: International Congress 2018 – COPD: immune regulation and therapeutic targets
Year: 2018

YS3: Thymic stromal lymphopoietin is a central regulator of anti-viral CD8+ T cell responses
Source: Lung Science Conference 2011 - Immune system dysregulation in chronic lung disease
Year: 2011

Levels of plasma tumour necrosis factor and soluble tumour necrosis factor receptor in patients with COPD and its relation to glucocorticoid receptor levels
Source: Annual Congress 2009 - Biomarkers and biology in COPD
Year: 2009

Current evidence of epidermal barrier dysfunction and thymic stromal lymphopoietin in the atopic march
Source: Eur Respir Rev 2014; 23: 292-298
Year: 2014



Down regulation of stromal cell-derived factor 1 (SDF-1/CXCL12) in lung tissue of patients with idiopathic pulmonary fibrosis
Source: Eur Respir J 2007; 30: Suppl. 51, 574s
Year: 2007

Inhibition of proliferation of lung cancer cells by CD40 signaling through tumor necrosis factor I
Source: Annual Congress 2008 - Biology and prognosis in thoracic oncology
Year: 2008

Analysing disease-specific variants of thymic stromal lymphopoietin (TSLP) in asthma
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

Interferon gamma decreases interleukin-8 production and neurokinin-1 receptor expression in lung alveolar epithelial cells
Source: Eur Respir J 2001; 18: Suppl. 33, 80s
Year: 2001

Expression of angiogenic growth factors and stromal cell derived factor-1/CXC chemokine receptor 4 (SDF-1/CXCL12 – CXCR4) biological axis in idiopathic pulmonary fibrosis: a lung tissue study
Source: Annual Congress 2008 - New insights into the pathogenesis of idiopathic pulmonary fibrosis and sarcoidosis
Year: 2008


Increased expression of angiogenic growth factor stromal cell derived factor-1 (SDF-1/CXCL12) in pleural fluid of patients with lung cancer: preliminary results
Source: Annual Congress 2008 - Biology and prognosis in thoracic oncology
Year: 2008

Serum thymic stromal lymphopoietin level depends on allergic profile in pediatric asthma
Source: Virtual Congress 2021 – Paediatric lung disease: novel mechanisms, methods and translational studies
Year: 2021