Ageing Smad3 KO mice develop emphysema and are resistant to Transforming growth factor-β1 (TGF-β1) mediated pulmonary fibrosis

P. Bonniaud, M. Kolb, T. Galt, J. Robertson, C. Robbins, A. B. Roberts, P. J. Margetts, J. Gauldie (Hamilton, Canada; Dijon, France; Wurzburg, Germany; Bethesda)

Source: Annual Congress 2003 - Animal models of lung injury: useful or not?
Session: Animal models of lung injury: useful or not?
Session type: Oral Presentation
Number: 3327
Disease area: Interstitial lung diseases

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P. Bonniaud, M. Kolb, T. Galt, J. Robertson, C. Robbins, A. B. Roberts, P. J. Margetts, J. Gauldie (Hamilton, Canada; Dijon, France; Wurzburg, Germany; Bethesda). Ageing Smad3 KO mice develop emphysema and are resistant to Transforming growth factor-β1 (TGF-β1) mediated pulmonary fibrosis. Eur Respir J 2003; 22: Suppl. 45, 3327

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