Erythropoietin (EPO) attenuates the immunohistochemical expression of autophagy antibodies in bleomycin (BLM), induced pulmonary fibrosis (PF) in rats

D. Tsavlis (Thessaloniki, Greece), D. Anestakis (Thessaloniki, Greece), P. Konstantinidou (Thessaloniki, Greece), K. Symeonidou (Thessaloniki, Greece), D. Koutsonikolas (Thessaloniki, Greece), A. Tzoumaka (Thessaloniki, Greece), E. Spandou (Thessaloniki, Greece)

Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis
Session: New mechanistic insights into pulmonary fibrosis
Session type: Thematic Poster
Number: 2425
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
D. Tsavlis (Thessaloniki, Greece), D. Anestakis (Thessaloniki, Greece), P. Konstantinidou (Thessaloniki, Greece), K. Symeonidou (Thessaloniki, Greece), D. Koutsonikolas (Thessaloniki, Greece), A. Tzoumaka (Thessaloniki, Greece), E. Spandou (Thessaloniki, Greece). Erythropoietin (EPO) attenuates the immunohistochemical expression of autophagy antibodies in bleomycin (BLM), induced pulmonary fibrosis (PF) in rats. 2425

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Erythropoietin (EPO) attenuates the immunohistochemical expression of tumor growth factor-ß (TGF-ß) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats
Source: International Congress 2018 – Pulmonary fibrosis: from models to patients
Year: 2018

Erythropoietin (EPO) attenuates the expression of its receptor (EPO-R) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats
Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Year: 2012

Erythropoietin (EPO) inhibits the bleomycin (BLM)-induced pulmonary fibrosis in rats
Source: Annual Congress 2010 - Emerging mechanisms in lung injury
Year: 2010

The effect of erythropoietin (EPO) on cyclooxygenase-2 (COX-2) and cytochrome-c (CYT-c) in the bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats
Source: Annual Congress 2011 - The ageing pulmonary interstitium
Year: 2011

Erythropoietin (EPO) inhibits the immunohistochemical expression of lysyl oxidase (LOX) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats
Source: International Congress 2015 – Pulmonary fibrosis: mechanisms of disease
Year: 2015

The attenuating effect of erythropoietin (EPO) on the expression of myeloperoxidase (MPO) in bleomycin-induced pulmonary fibrosis in rats
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013

Post-treatment with the heat shock protein 90 (hsp90) inhibitor, AUY-922, reduces lung hsp90 tyrosine (Y) phosphorylation and pulmonary inflammation in LPS-induced acute lung injury (ALI) in mice
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013

Hepatocyte growth factor (HGF) expression in bronchoveolar lower (BAL) does not confirm its anti-fibrotic activity in interstitial lung diseases (ILD)
Source: Annual Congress 2012 - Idiopathic pulmonary fibrosis
Year: 2012

Bleomycin induced lung fibrosis in mice is attenuated by a new somatostatin analog
Source: Annual Congress 2006 - Matrix remodelling at the interface of lung fibrosis and emphysema
Year: 2006


Aminoguanidine attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of heat shock protein 47 and TGF-β1 expression
Source: Annual Congress 2008 - Animal models of pulmonary fibrosis: mechanisms and therapies
Year: 2008


Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats
Source: Eur Respir J 2003 Dec 01;22(6):900-905
Year: 2003



Disruption of Nrf2 enhances susceptibility to pulmonary fibrosis induced by bleomycin in mice
Source: Annual Congress 2011 - The ageing pulmonary interstitium
Year: 2011

Tankyrase(TNKS) inhibiting autophagy promotes the TGF-ß induced EMT process in vitro and Bleomycin(BLM) induced pulmonary fibrosis in rats
Source: International Congress 2019 – Translational aspects of idiopathic pulmonary fibrosis
Year: 2019

Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis
Source: Eur Respir J 2004; 24: 57-65
Year: 2004



Fas Ligand (FasL) expressed on alveolar lymphocytes (AL) plays role in progression of interstitial lung diseases (ILD) but not in local induction of immune cells apoptosis
Source: Eur Respir J 2005; 26: Suppl. 49, 542s
Year: 2005

TGF-beta-dependent inhibitor of DNA protein (Id) expression in lung fibrosis
Source: Eur Respir J 2006; 28: Suppl. 50, 521s
Year: 2006

Attenuation by oral N-acetylcysteine of bleomycin-induced lung injury in rats
Source: Eur Respir J 2001; 17: 1228-1235
Year: 2001



Enhanced expression of interleukin 8 (CXCL8) in cystic fibrosis (CF) airway epithelial (AE) cells
Source: Annual Congress 2013 –Cystic fibrosis: basic and applied science
Year: 2013


Romidepsin (FK228) target focal adhesion kinase (FAK) expression in lung fibrosis
Source: International Congress 2015 – Pulmonary fibrosis: mechanisms of disease
Year: 2015


The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats
Source: Eur Respir J 2002; 19: 1124-1127
Year: 2002