Cigarette smoke induce Epithelial-Derived Inflammation through activating autophagy via RAGE signaling in bronchial epithelial cells.

C. Lin (Changhua, Taiwan), Y. Li (Changhua, Taiwan), H. Chang (Changhua, Taiwan), Y. Ching (Changhua, Taiwan), S. Lin (Changhua, Taiwan)

Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
C. Lin (Changhua, Taiwan), Y. Li (Changhua, Taiwan), H. Chang (Changhua, Taiwan), Y. Ching (Changhua, Taiwan), S. Lin (Changhua, Taiwan). Cigarette smoke induce Epithelial-Derived Inflammation through activating autophagy via RAGE signaling in bronchial epithelial cells.. 2397

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Cigarette smoke induces mitochondrial dysfunction via PKCd-p66Shc signaling pathway in human bronchial epithelial cells
Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium
Year: 2018

Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and the induction of inflammasome
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011

RAGE blocking ameliorates cigarette smoke extract-induced human alveolar tpye II epithelial cell injury via RAGE-mediated redox sensitive DAMP signaling through Nrf2
Source: International Congress 2018 – COPD: immune regulation and therapeutic targets
Year: 2018

Cigarette smoke impairs Sirt1 activity and promotes pro-inflammatory responses in bronchial epithelial cells
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

The AMPK-TSC1/2-mTOR signaling pathway regulates cigarette smoking-induced inflammation and apoptosis in airway epithelial cells
Source: International Congress 2015 – Molecular pathways of lung injury due to tobacco-related products
Year: 2015


Cigarette smoke augments MUC5AC mucin production via TLR3-EGFR pathway in airway epithelial cells
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013


Cigarette Smoke upregulates Notch1 signaling pathway in lung adenocarcinoma
Source: Virtual Congress 2020 – Effects of environmental exposures on lung pathology
Year: 2020


Cigarette smoke decreases E-Cadherin expression downregulating FoxO3 in lung epithelial cells
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD
Year: 2019

Recurrent cigarette smoke exposure impairs SIRT1 shuttling in bronchial epithelial cells
Source: International Congress 2016 – Translational studies in lung disease
Year: 2016

Cigarette smoke modulates the PKAc-associated cross-coupling between NF-kB and glucocorticoid receptor in primary small airway epithelial cells
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013

Role of aberrant Wnt signaling in the lung epithelial response to cigarette smoke in COPD
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011

Cigarette smoke increases TLR4 expression and modifies LPS mediated responses in airway epithelial cells
Source: Annual Congress 2007 - Epithelial networks in the airways
Year: 2007


Cigarette smoke impairs autophagic flux in bronchial epithelial cells
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

Quercetin attenuates inflammation in cigarette smoke stimulated airway epithelial cells: Possible involvement of autophagy
Source: Annual Congress 2013 –New drugs in respiratory medicine
Year: 2013


Ghrelin inhibits interleukin-6 production induced by cigarette smoke extract in the bronchial epithelial cells via NF-κB pathway
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

Cigarette smoke suppresses mast cell maturation and cytokine release independent of TLR4 signaling
Source: Annual Congress 2012 - Basic and translational studies in COPD
Year: 2012

Downregulation of lysosome-associated membrane protein-2A accelerates cigarette smoke extract-induced aging and apoptosis in human bronchial epithelial cells
Source: International Congress 2019 – Cellular responses and cell therapy in lung injury and repair
Year: 2019

Cigarette smoke alters the expression of the pro-inflammatory LTB4 receptor and increases the neutrophil adhesion in bronchial epithelial cells
Source: Annual Congress 2011 - Epithelial cell biology
Year: 2011

Carbocysteine restores the expression and the activation of TLR4 altered by cigarette smoke extracts in bronchial epithelial cells
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

Cigarette smoke upregulating the expression of miR 21 increases IL-8 in airway epithelial cells
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018