Genetic analysis of antigen-induced airway manifestations of asthma using recombinant congenic mouse strains

A. J. M. Van Oosterhout, P. V. Jeurink, P. C. Groot, G. A. Hofman, F. P. Nijkamp, P. Demant (Utrecht, Amsterdam, The Netherlands)

Source: Annual Congress 2003 - Immunology and airway reactivity in animal models of allergic asthma
Session: Immunology and airway reactivity in animal models of allergic asthma
Session type: Thematic Poster Session
Number: 3046
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. J. M. Van Oosterhout, P. V. Jeurink, P. C. Groot, G. A. Hofman, F. P. Nijkamp, P. Demant (Utrecht, Amsterdam, The Netherlands). Genetic analysis of antigen-induced airway manifestations of asthma using recombinant congenic mouse strains. Eur Respir J 2003; 22: Suppl. 45, 3046

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Allergen-induced inflammation and airway responsiveness in a mouse model of asthma: comparison between C57BL/6 and Th2-prone BALB/c mice
Source: Eur Respir J 2003; 22: Suppl. 45, 484s
Year: 2003

ST2 gene knockout attenuates allergic airways disease
Source: Annual Congress 2006 - Immunological mechanisms in cell recruitment to the lungs
Year: 2006


Analysis of mucus production in mouse models of allergic asthma
Source: Annual Congress 2010 - Asthma: basic science and clinical studies
Year: 2010

Analysis of the airway transcriptome in two rat strains of differing airway responsiveness
Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in chronic and acute airway diseases
Year: 2010

Murine models of asthma
Source: Eur Respir J 2003; 22: 374-382
Year: 2003



Models of asthma employing ovalbumin in rats and mice: similarities and differences compared with patient asthma
Source: Annual Congress 2005 - PG11 - Experimental models for COPD and asthma
Year: 2005


Treatment with gp120 reduces AHR and airway inflammation in a humanized mouse model of asthma bronchiale
Source: Annual Congress 2010 - Asthma: clinical aspects and treatment
Year: 2010


Dose-dependent effects of muIL-13Rα2, a potent IL-13 neutraliser, on the phenotype of an acute allergic airways inflammation model in BALB/c mice
Source: Annual Congress 2004 - Animal models of asthma and chronic bronchitis and their relevance in pulmonary pharmacology
Year: 2004


Improving of experimental allergic asthma by decreased Th2 responses in OGR-1 knockout mice
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


Effects of OVA-induced allergic airway inflammation and remodeling in mice in three distinct asthma models
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


Allergic airway inflammation in mice: similarities and differences with human asthma
Source: Annual Congress 2007 - Lunchtime programme: of mice, man and cell cultures - discussing different approaches in experimental lung research
Year: 2007

Effects of IL-4Rα blockade on lung inflammation and airway hyperresponsiveness using Mu317RAXMu, a murine surrogate for AMG 317, in a treatment model of cockroach allergen-induced asthma in mice
Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation
Year: 2008

Characterisation of type two immune responses in a murine model of allergic airway disease
Source: Virtual Congress 2020 – Scientific advances in airway pharmacology
Year: 2020


Transgenic mice overexpressing IL-18 display increased IL-13 in the airways but no changes of the airway hyperresponsiveness in a murine model of late-phase asthma: evidence for a dual role of IL-18 on mucosal Th1/Th2 responses
Source: Eur Respir J 2002; 20: Suppl. 38, 1s
Year: 2002

Deficiency of MMP-19 promotes allergen-induced eosinophil burden and airway responsiveness in mice
Source: Annual Congress 2007 - Regulation of allergic airway inflammation in animal models of asthma
Year: 2007



Disruption of CD44 variant 6 abolished bronchial hyperresponsiveness, inflammation and mast cell myositis in a murine model of asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 217s
Year: 2006

Development of IL-33-induced asthmatic airway inflammation in human IL-3/GM-CSF/IL-5-transgenic NOG mice
Source: International Congress 2017 – "Alarming" immunological patterns in asthma
Year: 2017


Intratracheally administered recombinant adenovirus carrying a novel mutated IκBα gene abrogates pulmonary eosinophil inflammation in a murine asthma model
Source: Eur Respir J 2006; 28: Suppl. 50, 225s
Year: 2006

VIP knockout mice show asthma-like airway hyper-reactivity, and inflammatory response to immunologic challenge
Source: Eur Respir J 2004; 24: Suppl. 48, 658s
Year: 2004

Role of mouse mast cell protease 4 in a murine model of allergic asthma
Source: Annual Congress 2007 - Regulation of allergic airway inflammation in animal models of asthma
Year: 2007