The uptake of ciclesonide-active metabolite and budesonide into human hepatocytes in vitro – the effect of serum protein binding Source: Eur Respir J 2006; 28: Suppl. 50, 434s Year: 2006
Pronounced tissue and plasma protein binding of ciclesonide is responsible for reduced pharmacodynamic potency in the lung Source: Eur Respir J 2007; 30: Suppl. 51, 351s Year: 2007
Pharmacokinetic factors affecting airway selectivity of inhaled steroids - role of intracellular esterification Source: Eur Respir J 2001; 18: Suppl. 33, 147s Year: 2001
Pharmacokinetic factors affecting airway selectivity of inhaled steroids – role of prodrug conversion and absorption Source: Eur Respir J 2004; 24: Suppl. 48, 347s Year: 2004
Low expression of cellular retinoic acid binding protein 2 and dysregulation of elastin expression in pulmonary emphysema fibroblasts Source: Annual Congress 2008 - Structural remodelling in COPD Year: 2008
Different inhaled corticosteroids altered lung microbiome and regulating the expression of PAF receptor as well as the phagocytosis function of macrophage Source: International Congress 2019 – Host-microbe interactions in lung disease and exacerbations Year: 2019
Effect of intermittent hypoxia on the expression of fatty acid binding proteins in human adipocytes and macrophages Source: Annual Congress 2011 - Obstructive sleep apnoea: inflammation and metabolism Year: 2011
Glucocorticoid potency correlates with transcriptional induction of a glucocorticoid regulated gene in human monocytes Source: Eur Respir J 2005; 26: Suppl. 49, 369s Year: 2005
Synergistic action of formoterol on budesonide-generated decrease of proteoglycan production by activated lung fibroblasts is mediated via β-adrenergic receptor and is dependent on glucocorticoid receptor Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
Low dose theophylline restores steroid insensitivity in PBMCs of steroid insensitive asthma patients Source: Eur Respir J 2004; 24: Suppl. 48, 347s Year: 2004
Corticosteroid effects on cell signalling Source: Eur Respir J 2006; 27: 413-426 Year: 2006
Serum surfactant protein D (SP-D) is a lung derived biomarker for COPD that is responsive to treatment with oral corticosteroids Source: Annual Congress 2008 - Biomarkers and disease assessment in COPD Year: 2008
The serum and glucocorticoid inducible kinase in alveolar transport regulation Source: Annual Congress 2009 - Novel regulators of alveolar liquid clearance Year: 2009
Reduced glucocorticoid receptor binding affinity in blood lymphocytes and monocytes of COPD patients Source: International Congress 2018 – Integrating pharmacological and non-pharmacological management in COPD: are we there yet? Year: 2018
Genomic markers of retinoid response in COPDe: R667 modulates genes associated inflammation and energy metabolism Source: Annual Congress 2007 - Novel genetic markers in pathology Year: 2007
Pulmonary targeting of ciclesonide and its active metabolite as determined in an ex-vivo rat receptor-binding assay Source: Eur Respir J 2002; 20: Suppl. 38, 618s Year: 2002
Partial characterisation of a PLA2 -like activity in human lipoprotein-free serum, which inactivates secreted phosphatidylcholine from cultured foetal rat type II cells Source: Eur Respir J 2004; 24: Suppl. 48, 108s Year: 2004
Regulation of corticosteroid binding globulin (CBG) in the inflammatory context of cystic fibrosis Source: Annual Congress 2011 - Cystic fibrosis: New aspects of diagnosis, inflammation and detecting exacerbation Year: 2011
Uptake, retention and metabolism of ciclesonide in human alveolar epithelial cells Source: Eur Respir J 2005; 26: Suppl. 49, 255s Year: 2005
Elevated serum IgE, oral corticosteroid dependence and IL-17/22 expression in highly neutrophilic asthma Source: Eur Respir J, 54 (5) 1900068; 10.1183/13993003.00068-2019 Year: 2019