The blockade of substance P receptors avoids the derangement of the vascular permeability during experimental donor-lung preservation

J. L. Arreola, L. M. Montaño, E. Flores, B. Sommer, M. H. Vargas (Mexico City, Mexico)

Source: Annual Congress 2003 - New developments in lung transplantation
Session: New developments in lung transplantation
Session type: Thematic Poster Session
Number: 2080
Disease area: Pulmonary vascular diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. L. Arreola, L. M. Montaño, E. Flores, B. Sommer, M. H. Vargas (Mexico City, Mexico). The blockade of substance P receptors avoids the derangement of the vascular permeability during experimental donor-lung preservation. Eur Respir J 2003; 22: Suppl. 45, 2080

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Optimization of tissue targeting properties of macitentan, a new dual endothelin receptor antagonist, improves its efficacy in a rat model of pulmonary fibrosis associated with pulmonary arterial hypertension
Source: Annual Congress 2011 - Treatment of human pulmonary hypertension
Year: 2011


NMDA receptor activation promotes vascular remodeling and pulmonary arterial hypertension
Source: International Congress 2018 – Pathobiology of pulmonary hypertension
Year: 2018

Echocardiographyc and histomorphometric assessment of the effects of pharmacological antagonism of endothelin receptors in the Sugen 5416/hypoxia rat model of pulmonary hypertension
Source: International Congress 2018 – Experimental research in pulmonary hypertension
Year: 2018

The inflammatory response of pulmonary vascular smooth muscle cells to bacterial endotoxin is sensitive to endothelin receptor antagonism
Source: Annual Congress 2012 - Phenotypes and mechanisms of treatment of asthma
Year: 2012

Endothelin-1 receptor antagonist prevents hyperoxia-induced parenchymal mechanical impairment in mice
Source: Eur Respir J 2004; 24: Suppl. 48, 334s
Year: 2004

Dual endothelin-1 receptor antagonism prevents chronic intermittent hypoxia-induced cardiovascular alterations in rats
Source: Annual Congress 2008 - Innovative treatments in sleep disordered breathing
Year: 2008

Role of airway smooth muscles in chronic airway inflammation and lung fibrosis and possible therapeutic potential of endothelin receptor antagonism
Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases
Year: 2010

The effect of estrogen and its receptor on hypoxic pulmonary vascular remodeling
Source: Eur Respir J 2006; 28: Suppl. 50, 658s
Year: 2006

PTEN reduces vascular endothelial growth factor–mediated vascular permeability in asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 581s
Year: 2005

Effects of AT1 receptor blockade on pulmonary and systemic manifestations in a COPD/emphysema mouse model
Source: Annual Congress 2009 - Preclinical models in drug development
Year: 2009

Effect of prior statin therapy on capillary permeability in the lungs after cardiac or vascular surgery
Source: Eur Respir J 2006; 27: 1026-1032
Year: 2006



The evaluation of airways mucosa vascular endothelial dysfunction
Source: Eur Respir J 2004; 24: Suppl. 48, 560s
Year: 2004

Endothelin-1-induced airway and parenchymal mechanical responses in guinea-pigs: the roles of ETA and ETB receptors
Source: Eur Respir J 2001; 17: 975-981
Year: 2001



Role of muscarinic receptors in airway inflammation and remodelling
Source: International Congress 2015 – Respiratory research in the Netherlands
Year: 2015


In vitro effects of vasodilatory drugs on BMPR2-silenced pulmonary microvascular endothelial cell function
Source: Virtual Congress 2021 – Pathogenesis and pathophysiology of pulmonary hypertension
Year: 2021


Iloprost protects against lung endothelial barrier dysfunction and vascular leak via Rap1
Source: Annual Congress 2009 - Crossing the line: alveolo-capillary barrier control in acute lung injury
Year: 2009



Loss of Bmp9 does not lead to spontaneous pulmonary hypertension, but attenuates vascular remodeling in experimental models
Source: Virtual Congress 2020 – Pathophysiology of pulmonary hypertension
Year: 2020


Mitochondrial dysfunction in airway epithelium increases pro-inflammatory IL-8, impairs barrier function and reduces glucocorticoid responsiveness
Source: Annual Congress 2011 - Lung cell biology
Year: 2011

CFTR dysfunction induces vascular endothelial growth factor synthesis in airway epithelium
Source: Eur Respir J 2013; 42: 1553-1562
Year: 2013



Effect of muscarinic receptors inhibition on cytokine release and inflammatory cells infiltration in the airway of cat as an animal model for COPD
Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD
Year: 2012