Paediatric severe asthma: a need for novel innate molecular phenotypes

Kristina Laubhahn, Bianca Schaub

Source: Eur Respir J, 54 (2) 1901459; 10.1183/13993003.01459-2019
Journal Issue: August
Disease area: Airway diseases, Paediatric lung diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Kristina Laubhahn, Bianca Schaub. Paediatric severe asthma: a need for novel innate molecular phenotypes. Eur Respir J, 54 (2) 1901459; 10.1183/13993003.01459-2019

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Paediatric respiratory epidemiology: asthma phenotypes – do they exist?
Source: Annual Congress 2009 - Paediatric year in review
Year: 2009


Identification of therapeutic targets for steroid-insensitive asthma using models that represent different clinical subtypes of disease
Source: International Congress 2016 – Asthma: mechanisms and biomarkers that promote clinical understanding
Year: 2016

Identification of molecular pathways in distinct asthma phenotypes identified in ADEPT
Source: International Congress 2015 – Novel strategies for the management of asthma, COPD and airway infections
Year: 2015

Identification of novel pathogenic mechanisms triggered by arginase activation in patients with COPD
Source: International Congress 2016 – Airway response to infection
Year: 2016


Pulmonary type-2 innate lymphoid cells in paediatric severe asthma: phenotype and response to steroids
Source: Eur Respir J, 54 (2) 1801809; 10.1183/13993003.01809-2018
Year: 2019



New phenotyping of corticosteroid-resistant asthma based on molecular mechanisms
Source: Annual Congress 2005 - Genetic polymorphisms and molecular mechanisms in asthma pathophysiology
Year: 2005


A novel evaluation of the impact of severe allergic asthma in children: The family perspective
Source: Annual Congress 2010 - Quality of life, asthma control and monitoring childhood asthma
Year: 2010

Integrating fingerprints: molecular phenotyping of severe asthma
Source: International Congress 2015 – Fingerprinting severe asthma
Year: 2015



PTX3 a marker of innate immune responses in the airways of asthmatics and COPD patients
Source: Annual Congress 2013 –Asthma: new mechanisms and markers
Year: 2013

LATE-BREAKING ABSTRACT: Associations and interactions of genetic polymorphisms in innate immunity genes with early viral infections and susceptibility to asthma and asthma-related phenotypes
Source: Annual Congress 2012 - Gene-environment treatment and asthma
Year: 2012


Translational research approaches for finding new therapeutic targets involved in viral-induced asthma and COPD exacerbation
Source: Research Seminar 2014 - Human translational medicine: a key bridge for the development of new drugs for severe asthma, COPD and ILD
Year: 2014


Care pathways for the selection of a biologic in severe asthma
Source: Eur Respir J, 50 (6) 1701782; 10.1183/13993003.01782-2017
Year: 2017



Defining asthma phenotypes
Source: Annual Congress 2013 –MS4 Asthma phenotypes and endotypes
Year: 2013

Assessment of innate immunity mediators in the lung of COPD patients: relation with disease manifestations
Source: Virtual Congress 2020 – Host-microbe interactions and their influence on lung disease onset and severity
Year: 2020


The role of infections in the induction of asthma: genetic and inflammatory drivers
Source: Annual Congress 2007 - PG24 - GRACE full-day course. From cough to asthma: the role of infection
Year: 2007

Occupational asthma: classical and novel causes and diagnostic approaches
Source: International Congress 2019 – PG13 Traditional and modern clinical approaches for diagnosis and management of occupational airways diseases
Year: 2019


Different innate neutrophil responses in controlled and uncontrolled asthma
Source: International Congress 2015 – Advances from translational research in respiratory infections
Year: 2015


Mechanisms of COPD exacerbations - molecular perspectives and pathophysiology
Source: ERS Satellites 2021
Year: 2021

Aetiology of exacerbations of asthma and COPD: new viruses, new mechanisms
Source: Annual Congress 2010 - Severe exacerbations in asthma and COPD: new causes, mechanisms and models of care
Year: 2010