Allergen-induced BDNF expression and neuronal remodeling contributes to airway hyperresponsiveness

S. Nijboer (Groningen, Netherlands), A. De Groot (Groningen, Netherlands), E. VohlíDalová (Groningen, Netherlands), I. Bos (Groningen, Netherlands), Y. Prakash (Rochester, United States of America), R. Gosens (Groningen, Netherlands), L. Kistemaker (Groningen, Netherlands)

Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control
Disease area: Airway diseases

Congress or journal article abstractWebcastSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Nijboer (Groningen, Netherlands), A. De Groot (Groningen, Netherlands), E. VohlíDalová (Groningen, Netherlands), I. Bos (Groningen, Netherlands), Y. Prakash (Rochester, United States of America), R. Gosens (Groningen, Netherlands), L. Kistemaker (Groningen, Netherlands). Allergen-induced BDNF expression and neuronal remodeling contributes to airway hyperresponsiveness. 5262

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The role of CCR5 in allergen-induced airway hyperresponsiveness and airway inflammation
Source: Annual Congress 2009 - Animal models of airways inflammation
Year: 2009

Increased arginase activity contributes to airway remodelling in chronic allergic asthma
Source: Eur Respir J 2011; 38: 318-328
Year: 2011



Airway epithelial cell P2Y6R-Expression is up-regulated during acute and chronic allergic inflammation and contributes via modulating of CXC8 and IL-6 secretion to development of airway remodelling
Source: Annual Congress 2010 - Pre-clinical models of airways disease
Year: 2010



Proto-oncogenes expression in airway remodelling in asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 159s
Year: 2001

A dual role of IL-6 signalling and STAT-3 activation on airway inflammation versus airway hyperresponsiveness in a murine model of asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 568s
Year: 2002

Osteopontin exacerbates airway hyperresponsiveness and lung remodeling in chronic asthma
Source: Annual Congress 2008 - Basic science in asthma and COPD
Year: 2008

Allergen-induced airway remodelling
Source: Eur Respir J 2007; 29: 1020-1032
Year: 2007



MMP-9 deficiency reduces airway inflammation and hyperresponsiveness in a mouse model of asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 20s
Year: 2001

ADAM33 is involved in post-natal airway hyperresponsiveness caused by maternal allergic airway inflammation
Source: International Congress 2018 – Paediatric asthma: new mechanisms and tools
Year: 2018


Increased expression of Lipocalin2 suppresses allergen-induced airway disease in mice
Source: Annual Congress 2008 - Novel mechanisms and targets of molecular pulmonary pathology
Year: 2008

TNF-α negatively modulates allergen-induced airway hyperresponsiveness through γδ T cells
Source: Eur Respir J 2002; 20: Suppl. 38, 27s
Year: 2002

Role of cytokines and chemokines in bronchial hyperresponsiveness and airway inflammation and remodelling
Source: Annual Congress 2007 - PG1 - Asthma: from bench to bedside
Year: 2007


Osteopontin deficiency protects from airway remodelling and hyperresponsiveness in chronic asthma
Source: Annual Congress 2009 - Novel mechanisms in the pathogenesis of asthma
Year: 2009


Role of macrophage migration inhibitory factor in ovalbumin-induced airway inflammation in rats
Source: Eur Respir J 2006; 27: 726-734
Year: 2006



The inflammation and the airway hyperresponsiveness in allergic asthma is inhibited by IL-10 dependent mechanism
Source: Annual Congress 2007 - Mouse models of allergic airway inflammation
Year: 2007


Allergen-induced airway responses
Source: Eur Respir J 2015; 46: 819-831
Year: 2015



Budesonide prevents but does not reverse sustained airway hyperresponsiveness in mice
Source: Eur Respir J 2008; 32: 970-978
Year: 2008



Inhaled doxycycline reduces allergen-induced airway inflammation, hyperresponsiveness and remodelling in mice
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Mechanisms of bronchial hyperresponsiveness in a clinical setting – putative role of smooth muscle
Source: Annual Congress 2005 - Role of the bronchial smooth muscle in regulating airway disease
Year: 2005

The induction of sub-epithelial myofibroblasts with contractility reveals a novel insight for airway hyperresponsiveness in asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 102s
Year: 2005