AZD1402/PRS-060, an inhaled Anticalin® IL-4Ra antagonist, potently inhibits IL-4 induced functional effects in human whole blood, which can be employed translationally in clinical studies.
K. Pardali (Gothenburg, Sweden), F. Jiang (Gothenburg, Sweden), M. Fitzgerald (Boston, United States of America), G. Matschiner (Boston, United States of America), D. Keeling (Gothenburg, Sweden)
Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control
Disease area: Airway diseases
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K. Pardali (Gothenburg, Sweden), F. Jiang (Gothenburg, Sweden), M. Fitzgerald (Boston, United States of America), G. Matschiner (Boston, United States of America), D. Keeling (Gothenburg, Sweden). AZD1402/PRS-060, an inhaled Anticalin® IL-4Ra antagonist, potently inhibits IL-4 induced functional effects in human whole blood, which can be employed translationally in clinical studies.. 5248
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