Increased sputum B cells in severe eosinophilic asthma: a local auto-inflammatory process

S. Lim (Singapore, Singapore), M. Mukherjee (Hamilton, Canada), N. Tan (Singapore, Singapore), W. Wong (Singapore, Singapore), V. Angeli (Singapore, Singapore), H. Lim (Singapore, Singapore)

Source: International Congress 2018 – Asthma, rhinitis and COPD: cells, mediators, biomarkers and genetics
Session: Asthma, rhinitis and COPD: cells, mediators, biomarkers and genetics
Session type: Thematic Poster
Number: 4459
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Lim (Singapore, Singapore), M. Mukherjee (Hamilton, Canada), N. Tan (Singapore, Singapore), W. Wong (Singapore, Singapore), V. Angeli (Singapore, Singapore), H. Lim (Singapore, Singapore). Increased sputum B cells in severe eosinophilic asthma: a local auto-inflammatory process. 4459

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Distribution of the cellular inflammatory pattern in induced sputum in an eosinophilic severe asthma population.
Source: International Congress 2019 – Airway diseases and blood cells
Year: 2019


Eosinophilic inflammation in sputum of poorly controlled asthmatics
Source: Eur Respir J 2002; 20: 1370-1377
Year: 2002



Inflammatory cell activation in eosinophilic and non-eosinophilic asthma
Source: Annual Congress 2006 - Immunology of the airways
Year: 2006


Treatment: how does inflammatory phenotype influence response to treatment in airway disease?
Source: Annual Congress 2007 - Inflammatory phenotypes in airway disease
Year: 2007


Cellular inflammatory pattern in induced sputum among patients with stable moderate or severe asthma
Source: Annual Congress 2010 - Biomarkers and Diagnosis of asthma and allergic respiratory diseases
Year: 2010


Distribution of sputum cellular phenotype in a large asthma cohort. Predicting factors for eosinophilic vs neutrophilic inflammation
Source: Annual Congress 2013 –Asthma and COPD: diseases with different phenotypes
Year: 2013


Bronchial hyper-responsiveness in chronic eosinophilic pneumonia is not correlated uniquely to local eosinophil infiltration
Source: Eur Respir J 2002; 20: Suppl. 38, 315s
Year: 2002

Conclusion: clinical phenotypes of asthma
Source: Annual Congress 2005 - Severe asthma: perception and management
Year: 2005

Airway eosinophilia is not related to clinical and functional findings in a large group of severe refractory asthmatics
Source: Annual Congress 2006 - Monitoring airway inflammation – exhaled markers vs induced sputum
Year: 2006


Biological role of lung-resident and inflammatory eosinophils in severe non-allergic eosinophilic asthma
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma
Year: 2019

Apoptotic response of eosinophils in chronic eosinophilic pneumonia
Source: Eur Respir J 2001; 17: 190-194
Year: 2001



Neutrophilic asthma features increased airway classical monocytes
Source: Virtual Congress 2020 – Phenotypes of asthma and COPD
Year: 2020


Sputum analysis reveals eosinophilic inflammation in difficult-to-control asthma patients with low blood eosinophils and FENO.
Source: Virtual Congress 2020 – Monoclonal antibodies; randomised controlled trials and real-world studies in asthma
Year: 2020


Evidence of mast-cell activation in a subset of patients with eosinophilic chronic obstructive pulmonary disease
Source: Eur Respir J 2002; 20: 325-331
Year: 2002



IL-33 mRNA in induced sputum cells from allergic rhinitis and asthma patients: a marker of Th-2 phenotype status?
Source: International Congress 2017 – Monitoring asthma control
Year: 2017

Induced sputum and blood T lymphocyte activation during exacerbations of severe asthmatics: the ISEA study
Source: Annual Congress 2006 - Towards understanding the pathogenesis of asthma
Year: 2006


Inflammatory subtypes in cough variant asthma (CVA): assessment using induced sputum
Source: Annual Congress 2007 - Asthma subphenotypes
Year: 2007


Reduced eosinophil apoptosis in induced sputum correlates with asthma severity
Source: Eur Respir J 2003; 22: 484-490
Year: 2003



Effects of omalizumab on markers of eosinophilic inflammation in patients with severe allergic asthma
Source: Annual Congress 2011 - Biomarkers and exacerbations of asthma and COPD
Year: 2011


Mechanisms of noneosinophilic asthma
Source: Annual Congress 2007 - Inflammatory phenotypes in airway disease
Year: 2007