Cholinergic muscarinic receptors and airway remodelling in severe asthma

F. Ricciardolo (Turin, Italy), A. Folino (Turin, Italy), V. Carriero (Turin, Italy), M. Bullone (Turin, Italy), M. Pieper ( Ingelheim am Rhein, Germany)

Source: International Congress 2018 – Studies on the mechanisms underlying airway disease
Session: Studies on the mechanisms underlying airway disease
Session type: Thematic Poster
Number: 4402
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
F. Ricciardolo (Turin, Italy), A. Folino (Turin, Italy), V. Carriero (Turin, Italy), M. Bullone (Turin, Italy), M. Pieper ( Ingelheim am Rhein, Germany). Cholinergic muscarinic receptors and airway remodelling in severe asthma. 4402

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Role of muscarinic receptors in airway inflammation and remodelling
Source: International Congress 2015 – Respiratory research in the Netherlands
Year: 2015


Increased airway responsiveness to beta-adrenergic agonists in asthmatic patients
Source: Eur Respir J 2005; 26: Suppl. 49, 582s
Year: 2005

The serotoninergic receptor subtype 5-HTR1B contributes to the pathogenesis of allergic airway inflammation
Source: Annual Congress 2012 - Cell culture and animal models of lung disease
Year: 2012

Interaction of the glutamatergic and nitrergic signaling system in the airway hyperreactivity
Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD
Year: 2012


Mice lacking both M2 and M3 muscarinic receptors display airway hyperresponsiveness (AHR) to serotonin
Source: Eur Respir J 2005; 26: Suppl. 49, 714s
Year: 2005

Airway hyperresponsiveness in offspring from mothers with allergic airway inflammation during pregnancy is muscarinic receptor and ADAM33 dependent.
Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes
Year: 2020


The muscarinic M3 receptor regulates allergen-induced airway remodeling in mice
Source: Annual Congress 2013 –Asthma drugs: new findings
Year: 2013


Late Breaking Abstract - Role of Muscarinic M3 receptors in bronchial remodelling of severe asthma
Source: International Congress 2017 – Late-breaking findings in asthma and COPD
Year: 2017


Attenuation of ozone-induced tachypnoea by activation of dopamine D2 receptors in the rat: involvement of vagal bronchopulmonary C fibres
Source: Eur Respir J 2001; 18: Suppl. 33, 408s
Year: 2001

Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in the airway remodeling induced by chronic airway inflammation in guinea pigs
Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II
Year: 2008

Involvement of NK1, 2 and 3 receptors on antigen-induced airway hyperresponsiveness and inflammation induced in guinea-pigs
Source: Eur Respir J 2001; 18: Suppl. 33, 246s
Year: 2001

Cholinergic tone and airway hyperresponsiveness in patients with persistent allergic asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 219s
Year: 2006

Role of airway smooth muscles in chronic airway inflammation and lung fibrosis and possible therapeutic potential of endothelin receptor antagonism
Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases
Year: 2010

Changes in muscarinic cholinergic receptor expression in human peripheral blood lymphocytes in allergic rhinitis patients
Source: Eur Respir J 2006; 28: Suppl. 50, 748s
Year: 2006

An oral selective M3 cholinergic receptor antagonist in COPD
Source: Eur Respir J 2006 Oct 01;28(4):772-780
Year: 2006



Beta 2-adrenergic receptor polymorphisms and bronchial hyperresponsiveness in asthmatic children
Source: Eur Respir J 2005; 26: Suppl. 49, 616s
Year: 2005

Airway responsiveness to beta-adrenergic agonist in smokers
Source: Eur Respir J 2004; 24: Suppl. 48, 341s
Year: 2004

Increased relaxation of immature airways to beta-2 agonists is related to the attenuated expression of postjunctional smooth muscle muscarinic M2 receptors
Source: Annual Congress 2004 - Understanding the complexity of how airways are regulated
Year: 2004


Modulation of cholinergic contractions of airway smooth muscle by cathinone: potential beneficial effects in airway diseases
Source: Eur Respir J 2008; 32: 579-584
Year: 2008