A major inflammatory cytokine TNF-a inhibits the ventilatory response to hypoxia

A. Klinnikova (St.-Petersburg, Russian Federation), G. Danilova (St.-Petersburg, Russian Federation), N. Alexandrova (St.-Petersburg, Russian Federation)

Source: International Congress 2018 – Triggers of acute lung injury: mechanical ventilation and oxygen levels
Session: Triggers of acute lung injury: mechanical ventilation and oxygen levels
Session type: Thematic Poster
Number: 4304
Disease area: Airway diseases, Respiratory critical care

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Klinnikova (St.-Petersburg, Russian Federation), G. Danilova (St.-Petersburg, Russian Federation), N. Alexandrova (St.-Petersburg, Russian Federation). A major inflammatory cytokine TNF-a inhibits the ventilatory response to hypoxia. 4304

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
A major inflammatory cytokine IL-1β inhibits the ventilatory response to hypoxia
Source: International Congress 2016 – Hypoxia, oxidative stress, and biomarkers in obstructive sleep apnoea
Year: 2016


The role of pro-inflammatory cytokine activation in perioperative lung injury
Source: Annual Congress 2004 - Mechanisms and biomarkers of ischaemia-reperfusion-induced lung injury: lessons learnt from lung transplantation
Year: 2004

Exaggerated IL-6 responses to LPS after viral airway infection in mice is mediated by endogenous TNF-a production
Source: Annual Congress 2007 - Immunological function in viral and nonviral pathogens
Year: 2007



TLR-4 downregulation in COPD impairs cytokine release from monocytes and Th1-lymphocytes in response to bacterial endotoxin
Source: Annual Congress 2009 - What is new in molecular pathology and functional genomics of neoplastic and non-neoplastic lung disease?
Year: 2009


Aerobic training modulates parenquimal inflammation via decreases of IL-4 and IL-5 release by inflammatory cells
Source: Annual Congress 2007 - Towards an understanding of asthma pathogenesis - novel in vitro assays and results from animal models
Year: 2007


Alveolar macrophage oxidative and pro-inflammatory cytokine activity in lung sarcoidosis
Source: Eur Respir J 2005; 26: Suppl. 49, 332s
Year: 2005

Influence of montelukast on T cell migration, production of Th2-type cytokines and proinflammatory cytokines
Source: Eur Respir J 2004; 24: Suppl. 48, 129s
Year: 2004

Dynamic of proinflammatory cytokines system and nonspecific markers of inflammation in patients with COPD before and after treatment with broncholitics
Source: Eur Respir J 2006; 28: Suppl. 50, 38s
Year: 2006

Endotoxin-induced release of the Th17-associated cytokine interleukin (IL)-26 in human neutrophils
Source: International Congress 2017 – Infection and exacerbation science
Year: 2017

Statins suppress LPS-induced proinflammatory cytokine production from human bronchial epithelial cells
Source: Annual Congress 2009 - Epithelial cell biology
Year: 2009


Injury induced inflammasome activation leading to IL-1b and lung inflammation depends on IL-17
Source: Annual Congress 2010 - Stem cells and growth factors in lung injury
Year: 2010

Airways inflammation and remodeling is inhibited by aerobic exercise via decreases of IL-4 and IL-5 release by inflammatory cells
Source: Annual Congress 2007 - Towards an understanding of asthma pathogenesis - novel in vitro assays and results from animal models
Year: 2007


The proinflammatory cytokine is important in determining the severity of asthma enhancing the inflammatory process
Source: Eur Respir J 2004; 24: Suppl. 48, 592s
Year: 2004

Hypoxia induces IL-18 and neutrophil influx in lung parenchyma possibly mediated by MIP-2
Source: Annual Congress 2012 - The many roads to lung injury
Year: 2012

Study of influence of interleukin-1b on cytokines production in inflammatory sites
Source: Annual Congress 2007 - Improving asthma therapy - new findings in established and experimental treatment modalities
Year: 2007


Involvement of nitric oxide, proinflammatory cytokines and effector cells in the inflammatory process in COPD patients
Source: Eur Respir J 2005; 26: Suppl. 49, 54s
Year: 2005

Role of proinflammatory cytokines IL-18 and IL-1β in bleomycin-induced lung injury in humans and mice
Source: Annual Congress 2009 - Mechanisms of pulmonary inflammation and fibrosis
Year: 2009

Inflammatory response to infectious pulmonary injury
Source: Eur Respir J 2003; 22: 10S-14S
Year: 2003



Pro-inflammatory cytokines stimulate airway mucus secretion in a rat model of COPD
Source: Eur Respir J 2001; 18: Suppl. 33, 520s
Year: 2001

Chemokinome characterization in human lung macrophages following stimulation with Th2-type cytokines IL-4 or IL-13
Source: Annual Congress 2012 - Update on neutrophil and macrophage function in COPD
Year: 2012