Effect of human neutrophil proteases on ex vivo small airway function Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung Year: 2013
Inhaled formulation of angiotensin-(1-7) produces lung protective effects in a model of chronic asthma. Source: International Congress 2018 – Identification of therapeutic targets for asthma Year: 2018
Effects of treatment with angiotensin-(1-7) on antigen sensitization of murine experimental model of asthma Source: International Congress 2019 – Modelling and monitoring of airway diseases Year: 2019
Anti-inflammatory effect of hypoxic signaling suppression in the severe COPD model. Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium Year: 2018
The effect of long term treatment with erdosteine on COPD: the Equalife study Source: Eur Respir J 2003; 22: Suppl. 45, 428s Year: 2003
Small airways function: evaluation in a population of adult patients with severe asthma and potential use as a response biomarker for anti-IL5 therapy Source: Virtual Congress 2020 – Monoclonal antibodies; randomised controlled trials and real-world studies in asthma Year: 2020
Effect of photobiomodulation on reduction of CD4STAT4 and CD4IFN-? and increased treg cells and IL-10 in an experimental model of COPD. Source: International Congress 2019 – Advances in COPD pharmacology Year: 2019
RP6503, a novel and selective PI3K δ/gamma inhibitor, potentiates the effect of steroids in pre-clinical models of COPD Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs Year: 2014
Favorable human safety, pharmacokinetics and pharmacodynamics of the autotaxin inhibitor GLPG1690, a potential new treatment in COPD Source: International Congress 2015 – Advances in the future treatment of COPD Year: 2015
Dose-FEV1 modeling to support future development of AZD2115, a dual acting bronchodilator for the treatment of COPD Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD Year: 2015
A single dose of a specific serinoprotease inhibitor attenuated the protease-antiprotease imbalance in an experimental model of emphysema Source: Annual Congress 2012 - The many roads to lung injury Year: 2012
SERCA2a gene therapy ameliorates pulmonary hypertension in a pig model: comparison of different delivery methods and therapeutic effect Source: Virtual Congress 2020 – Pathophysiology of pulmonary hypertension Year: 2020
Pharmacological profile and efficacy of GLPG1690, a novel ATX inhibitor for COPD treatment Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD Year: 2015
Effect of mast cells degranulation blockade on the inflammatory response outcome in the COPD model Source: International Congress 2016 – New signalling pathways in COPD Year: 2016
Results of a phase 2a clinical trial with a peptide inhibitor of MARCKS protein indicate improvement of indices of bronchitis and lung function in patients with COPD Source: Annual Congress 2011 - Novel mechanisms in COPD Year: 2011
Effect of low level light therapy (LLLT) on an experimental model of LPS-induced lung inflammation Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD Year: 2012
The effect of mast cell stabilisation in a large animal model of pulmonary fibrosis Source: International Congress 2019 – Translational aspects of idiopathic pulmonary fibrosis Year: 2019
An inhaled “bifunctional” dual PDE3/4 inhibitor provides additional short-term improvements in lung function compared to existing classes of bronchodilator: implications for future treatment of COPD Source: Eur Respir J, 52 (5) 1801675; 10.1183/13993003.01675-2018 Year: 2018
Dual-phenotype mouse model of COPD study suggest combined therapy targeting G-CSF and IL-17A could treat COPD. Source: International Congress 2017 – Novel molecular and genetic targets in COPD Year: 2017
The effects of endogenous and exogenous vitamin D on the rate of mature elastin degradation in COPD patients Source: International Congress 2016 – New signalling pathways in COPD Year: 2016