Increased CTGF expression of circulating fibrocytes in asthmatic patients with severe OSA - the role of HIF-1a and HDAC7

T. Wang (Taipei, Taiwan), Y. Lo (Taipei, Taiwan), C. Wang (Taipei, Taiwan), H. Kuo (Taipei, Taiwan)

Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Disease area: Airway diseases, Sleep and breathing disorders

Congress or journal article abstractWebcastSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
T. Wang (Taipei, Taiwan), Y. Lo (Taipei, Taiwan), C. Wang (Taipei, Taiwan), H. Kuo (Taipei, Taiwan). Increased CTGF expression of circulating fibrocytes in asthmatic patients with severe OSA - the role of HIF-1a and HDAC7. 2186

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Reduced expression of the transcription factor KLF4 in COPD macrophages is associated with dysfunctional differentiation
Source: International Congress 2017 – Translational studies of lung disease
Year: 2017

Activin-A expression is increased in severe asthma and is involved in tissue angiogenesis
Source: Annual Congress 2012 - Asthma and COPD: understanding through mechanisms
Year: 2012

Decreased expression of VEGFR-2 mRNA in pulmonary vessels of COPD patients
Source: Annual Congress 2009 - Hot topics in molecular pathology and functional genomics of COPD
Year: 2009

Increased expression of MMP-2 in COPD
Source: Eur Respir J 2005; 26: Suppl. 49, 361s
Year: 2005

Carbocisteine in vivo reduces circulating miR-21 and IL-8 in exacerbated COPD patients
Source: International Congress 2019 – COPD clinical trials: inhaled and oral therapies
Year: 2019

Increased levels of vascular endothelial growth factor in induced sputum in asthmatic patients
Source: Eur Respir J 2002; 20: Suppl. 38, 1s
Year: 2002

High ICAM-1 gene expression in pulmonary fibroblasts of COPD patients
Source: Eur Respir J 2004; 24: Suppl. 48, 454s
Year: 2004

Reduced bronchial epithelial Smad7 protein expression in COPD
Source: Eur Respir J 2005; 26: Suppl. 49, 3s
Year: 2005

Reduced expression of CD44 on lung macrophages from patients with COPD
Source: Annual Congress 2010 - Novel markers of lung injury
Year: 2010


Increased levels of circulating endothelial progenitor cells during exacerbations of COPD
Source: Annual Congress 2007 - Biomarkers and assessment of COPD
Year: 2007



Elevated expression of TLR4 and HBD2 but decreased levels of IP-10 in COPD with severe exacerbation
Source: Annual Congress 2008 - Inflammatory trigger mechanisms in asthma and COPD
Year: 2008

Increased interleukin-5 mRNA expression and Bcl-2 depended eosinophils apoptosis suppression in atopic asthmatics
Source: Eur Respir J 2003; 22: Suppl. 45, 455s
Year: 2003

The expression of CD39 mRNA is altered in peripheral blood of patients with allergic asthma
Source: Annual Congress 2013 –Genetics and mechanisms of, and tests for, allergy
Year: 2013

Vascular endothelial growth factor (VEGF) levels in induced sputum and plasma in asymptomatic and COPD smokers. Correlation with airway and systemic inflammation
Source: Eur Respir J 2006; 28: Suppl. 50, 652s
Year: 2006

HIF dependent regulation of S100A4 protein in COPD induced vascular remodelling
Source: Annual Congress 2010 - Pulmonary circulation I
Year: 2010

Neovascularisation in asthma: Altered angiogenic potential of ASM cells from asthmatic patients
Source: Annual Congress 2012 - Molecular biology of pro- and anti-inflammatory responses in the lung
Year: 2012

The involvement of thrombospondin-1 in COPD pathogenesis through IL-8 production
Source: Annual Congress 2013 –COPD: experimental biology
Year: 2013

Genes affecting mRNA stability and metalloproteinase inhibitor RECK are down-regulated in patients with COPD
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013



Decreased BCL-2 expression in alveolar macrophages of patients with idiopathic pulmonary fibrosis
Source: Annual Congress 2010 - Biomarkers in diffuse parenchymal lung disease
Year: 2010


Expression of CD38 and its participation in formation of endothelial dysfunction in patients with bronchial asthma
Source: Annual Congress 2011 - New mechanisms in airway disease
Year: 2011