Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging

I. Fernandez (München, Germany), N. Sun (Neuherberg, Germany), M. Wei (Neuherberg, Germany), M. Witting (Neuherberg, Germany), M. Aichler (Neuherberg, Germany), S. Verleden (Leuven, Belgium), P. Schmitt-Kopplin (Neuherberg, Germany), A. Walch (Neuherberg, Germany), O. Eickelberg (München, Germany)

Source: International Congress 2018 – Respiratory muscles and lung function: from healthy subjects to patients
Session: Respiratory muscles and lung function: from healthy subjects to patients
Session type: Oral Presentation
Number: 2151
Disease area: Interstitial lung diseases

Congress or journal article abstractWebcastSlide presentation

Rating: 4
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
I. Fernandez (München, Germany), N. Sun (Neuherberg, Germany), M. Wei (Neuherberg, Germany), M. Witting (Neuherberg, Germany), M. Aichler (Neuherberg, Germany), S. Verleden (Leuven, Belgium), P. Schmitt-Kopplin (Neuherberg, Germany), A. Walch (Neuherberg, Germany), O. Eickelberg (München, Germany). Pharmacometabolic effect of pirfenidone treatment in IPF detected by high resolution MALDI-FTICR imaging. 2151

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Assessment of a new magnetic resonance imaging (MRI)-scoring- system for pulmonary changes in patients with cystic fibrosis (CF) – comparison with clinical parameters and high resolution computed tomography (HRCT)
Source: Annual Congress 2006 - New modalities and application in imaging of the chest
Year: 2006


The prevalence and extent of bronchiectasis on high resolution CT scanning in patients with COPD
Source: Eur Respir J 2002; 20: Suppl. 38, 600s
Year: 2002

Lacunarity analysis enables detection of emphysema progression in COPD smokers using MR imaging of inhaled hyperpolarized helium
Source: Annual Congress 2007 - Imaging modalities in asthma, COPD and emphysema
Year: 2007


Effect of low dose pirfenidone on survival and lung function decline in patients with idiopathic pulmonary fibrosis (IPF): results from a real life study
Source: Virtual Congress 2021 – News in treatment and diagnosis of idiopathic interstitial pneumonia
Year: 2021


The relationship between the presence of bronchiectasis on high resolution CT scanning and lower airway bacterial colonisation in patients with COPD
Source: Eur Respir J 2002; 20: Suppl. 38, 158s
Year: 2002

Comparison of in-vivo lung morphometry models from multiple b-value diffusion-weighted MRI in healthy controls, IPF and COPD patients
Source: International Congress 2017 – Novel imaging findings characterising various lung diseases and their prognoses
Year: 2017



Quantitative multivolume proton-magnetic resonance imaging in patients with cystic fibrosis lung disease: comparison with clinical indicators
Source: Eur Respir J, 53 (5) 1702020; 10.1183/13993003.02020-2017
Year: 2019



Differential diagnosis between pulmonary fibrosis and lung emphysema by analysis of pixel density distribution of high resolution computed tomography (HRCT)
Source: Eur Respir J 2004; 24: Suppl. 48, 68s
Year: 2004

Quantitative measurement of airway dimensions on high resolution CT scans and detection of structural lung damage in children who have cystic fibrosis
Source: Eur Respir J 2002; 20: Suppl. 38, 20s
Year: 2002

Late Breaking Abstract - A PET imaging study to confirm target engagement in the lungs of patients with IPF following a single dose of a novel inhaled avß6 integrin inhibitor
Source: International Congress 2019 – Idiopathic pulmonary fibrosis and surroundings
Year: 2019



MMP2 probe based on in vivo imaging technique for tracking ALI/ARDS in mice
Source: Virtual Congress 2021 – COVID19, acute respiratory failure and basic science
Year: 2021


High resolution computed tomography quantitation of emphysema is correlated with selected lung function tests values in patients with stable COPD
Source: Annual Congress 2010 - Asthma and COPD: understanding through monitoring
Year: 2010

The magnitude of pirfenidone treatment effect in patients with idiopathic pulmonary fibrosis (IPF): A pooled analysis of outcomes in the CAPACITY (CAP) studies
Source: Annual Congress 2010 - New insights in the treatment of idiopathic pulmonary fibrosis
Year: 2010

Visualization of intralobular minimal change of emphysema using ultra high resolution CT
Source: Annual Congress 2010 - Infection, inflammation and destruction
Year: 2010


High resolution computed tomography (HRCT) findings before and after treatment with Interferon gamma - 1b (IFN-γ) or colchicine in idiopathic pulmonary fibrosis (IPF) patients
Source: Eur Respir J 2003; 22: Suppl. 45, 592s
Year: 2003

Assessment of chest magnetic resonance imaging in non-cystic fibrosis chronic lung disease: comparison to high-resolution computed tomography and correlation with clinical and pulmonary function data
Source: Annual Congress 2009 - Paediatric lung function, imaging and methodology in health and disease
Year: 2009


In vivo optical imaging for low-risk microscopic diagnosis of IPF
Source: International Congress 2018 – News on the diagnosis of idiopathic interstitial pneumonia
Year: 2018

Ventilation heterogeneity assessed in patients with mild cystic fibrosis and asthma using Hyperpolarised gas MRI histogram analysis
Source: International Congress 2017 – Novel imaging findings characterising various lung diseases and their prognoses
Year: 2017



Quantitative multivolume magnetic resonance imaging (1H-MRI) in patients with cystic fibrosis (CF) lung disease:comparison with FEV1 and lung clearance index (LCI)
Source: International Congress 2017 – Cystic fibrosis: monitoring and biomarkers
Year: 2017

Comparison of high resolution computerized tomography (HRCT) of the chest and pulmonary function testing in evaluating the effect of tobramycin solution for inhalation in cystic fibrosis (CF) patients
Source: Eur Respir J 2004; 24: Suppl. 48, 387s
Year: 2004