The role of basal cells in the aberrant repair of the epithelium in COPD

Renat R. Shaykhiev (New York, United States of America)

Source: International Congress 2017 – Lung tissue repair and remodelling in chronic lung diseases: mechanisms and therapeutic approaches
Disease area: Airway diseases

Webcast

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Renat R. Shaykhiev (New York, United States of America). The role of basal cells in the aberrant repair of the epithelium in COPD. International Congress 2017 – Lung tissue repair and remodelling in chronic lung diseases: mechanisms and therapeutic approaches

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The role of altered stem cell function in airway and alveolar repair and remodelling in COPD
Source: Eur Respir Monogr 2021; 91: 322-339
Year: 2021


Different role of p21 in the remodelling of central and peripheral airway epithelium in smokers with and without COPD
Source: Annual Congress 2010 - Novel insights into the pathophysiology of asthma and COPD
Year: 2010

COPD exacerbation influence on chromatin organization in bronchial epithelium cells
Source: Eur Respir J 2006; 28: Suppl. 50, 747s
Year: 2006

The role of bronchial epithelial cells in COVID-19 infection and pathogenesis
Source: Virtual Congress 2020 – (Re-)discovering the small airway epithelium in COVID-19, fibrosing lung diseases and pulmonary regeneration
Year: 2020


Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity
Source: ERJ Open Res, 7 (1) 00254-2020; 10.1183/23120541.00254-2020
Year: 2021



Changes in human airway cells transcriptome during epithelial wound repair
Source: Virtual Congress 2021 – Advanced in vitro models for drug discovery
Year: 2021


Altered phenotype of COPD primary fibroblasts from airway and alveolar tissues: proliferation and apoptosis.
Source: International Congress 2019 – Research and innovation in airway diseases
Year: 2019

A role for PAR-1 in bronchial epithelial repair
Source: Eur Respir J 2005; 26: Suppl. 49, 556s
Year: 2005

Wnt/ß-catenin signalling is upregulated in the COPD bronchial epithelium.
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD
Year: 2019


The role of the COPD susceptibility gene FAM13A in barrier function and pro-inflammatory responses of human airway epithelial cells
Source: ERS Lung Science Conference 2020
Year: 2020

Interleukin-1alpha drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD
Source: Eur Respir J 2016; 48: 359-369
Year: 2016



Upregulation of the production of TGF-β and IL-4 and downregulation of IL-6 by apoptotic human bronchial epithelial cells: possible role in regulation of epithelial repair following acute lung injury
Source: Eur Respir J 2001; 18: Suppl. 33, 477s
Year: 2001

Altered iron metabolism and elevated cellular senescence in COPD small airway epithelial cells
Source: Virtual Congress 2020 – Metabolic alterations and ageing in lung disease
Year: 2020




Evidence for the involvement of lipofibroblasts, airway smooth muscle cells and FGF10 signalling in lung repair
Source: Eur Respir Monogr 2021; 91: 99-113
Year: 2021


Do characteristic airway epithelial change precede the development of lung fibrosis? Ectopic epithelial marker protein expression in bleomycin induced fibrosis replicates that seen in bronchiolized epithelium in IPF
Source: Annual Congress 2012 - Cell culture and animal models of lung disease
Year: 2012

The role of resident lung mesenchymal stromal cells in normal and aberrant lung development
Source: Virtual Congress 2020 – Cellular involvement in lung injury
Year: 2020




PTEN deficiency in alveolar type 2 cells accelerates cellular senescence, disrupts epithelial–mesenchymal and mitochondrial homeostasis, and induces age-related emphysema
Source: International Congress 2019 – Cellular metabolism and immune senescence in lung pathology
Year: 2019



Nuclear expression of Ku86, a DNA repair protein, is decreased in bronchiolar epithelium of COPD patients
Source: Eur Respir J 2004; 24: Suppl. 48, 458s
Year: 2004

Human bronchial epithelium orchestrates dendritic cell activation in severe asthma
Source: Eur Respir J , 49 (3) 1602399; DOI: 10.1183/13993003.02399-2016
Year: 2017