TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts

A. M. Kapoun, Y. Wang, N. J. Gaspar, D. Damm, Y. W. Liu, G. O‘Young, R. T. White, A. Lam, D. Quon, F. Q. Wen, S. I. Rennard, L. S. Higgins (Fremont, Omaha, United States Of America)

Source: Annual Congress 2004 - Translation of lung inflammation from bench to bedside

Session: Translation of lung inflammation from bench to bedside
Session type: Poster Discussion
Number: 4401

Disease area: Interstitial lung diseases

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A. M. Kapoun, Y. Wang, N. J. Gaspar, D. Damm, Y. W. Liu, G. O‘Young, R. T. White, A. Lam, D. Quon, F. Q. Wen, S. I. Rennard, L. S. Higgins (Fremont, Omaha, United States Of America). TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts. Eur Respir J 2004; 24: Suppl. 48, 4401

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