Cytosolic phospholipase A2 type IVβ induces interleukin – 8 and cyclooxygenase -2 gene expression but does not influence IL-16 and heme oxygenase-1 transcription in human lung cells

R. Pawliczak, C. Logun, G. Woszczek, A. Ptasinska, M. L. Kowalski, T. Wu, J. H. Shelhamer (Lodz, Poland; Bethesda, Pittsburgh, United States Of America)

Source: Annual Congress 2004 - Inflammation and remodelling in human lungs
Session: Inflammation and remodelling in human lungs
Session type: Oral Presentation
Number: 4179
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Pawliczak, C. Logun, G. Woszczek, A. Ptasinska, M. L. Kowalski, T. Wu, J. H. Shelhamer (Lodz, Poland; Bethesda, Pittsburgh, United States Of America). Cytosolic phospholipase A2 type IVβ induces interleukin – 8 and cyclooxygenase -2 gene expression but does not influence IL-16 and heme oxygenase-1 transcription in human lung cells. Eur Respir J 2004; 24: Suppl. 48, 4179

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
IL-8 and COX-2 expression is regulated through cPLA2-derived arachidonate metabolites in human lung cells
Source: Annual Congress 2003 - Intracellular signalling and regulation of cytokine production
Year: 2003


Role of arginase and NOS2 in the regulation of CCL18 release
Source: Annual Congress 2008 - Airway cell biology and immunology
Year: 2008


Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells
Source: Eur Respir J 2004; 24: Suppl. 48, 29s
Year: 2004

PDK1/RSK1-dependent C/EBPß activation is involved in thrombin-induced expression of orosomucoid 1-like 3 (ORMDL3) and IL-8/CXCL8 in human lung epithelial cells
Source: International Congress 2017 – Asthma: mechanisms and treatment
Year: 2017


CCL5 (RANTES) inhibits TGF-β1-induced collagen production in human bronchial epithelial cells by action of Smad protein
Source: Annual Congress 2009 - New results in molecular pathology and functional genomics of non-neoplastic lung diseases
Year: 2009

Inhibition of histone acetyltransferases attenuates cytokine and LPS-induced up-regulation of arginase in rat alveolar macrophages
Source: Eur Respir J 2006; 28: Suppl. 50, 662s
Year: 2006

p38 MAPK/MSK1/CREB signal pathway involves in transforming growth factor-β-induced heme oxygenase-1 expression in human lung epithelial cells
Source: Eur Respir J 2007; 30: Suppl. 51, 544s
Year: 2007

Peroxiredoxin 6 attenuates lipopolysaccharide-induced plasminogen activatro inhibitor 1 expression by regulating autophagy
Source: Annual Congress 2012 - Lung injury and repair: reactive oxygen species and beyond
Year: 2012

Calprotectin stimulates interleukin 8 release from A549 cells
Source: Eur Respir J 2002; 20: Suppl. 38, 372s
Year: 2002

Dexamethasone inhibits LPS-induced expression of human β-defensin-2 via down-regulation of TLR4
Source: Eur Respir J 2003; 22: Suppl. 45, 562s
Year: 2003

IL-13 enhances GSNO reductase activity and decreases intracellular S-nitrosothiols in lung epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 103s
Year: 2006

Increased COX-1 and COX-2 mRNA expression and prostaglandin E2 production by dendritic cells from patients with asthma
Source: Annual Congress 2003 - Intracellular signalling and regulation of cytokine production
Year: 2003


Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells
Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms
Year: 2020

IL-13 induces glucocorticoid resistance in iNOS expression and activity in human airway epithelial cells (HAECs)
Source: International Congress 2017 – New insights into pathogenesis of lung disease 
Year: 2017


Proteinase-activated receptor-2 (PAR2) activation on human lung fibroblasts increases IL-6 & IL-8 mRNA expression
Source: Annual Congress 2003 - Mechanisms of lung injury: from bench to bedside
Year: 2003


Activation of E-prostanoid4 and E-prostanoid2 receptors inhibits TNF-α release from human alveolar macrophages
Source: Eur Respir J 2007; 29: 986-994
Year: 2007



Apocynin augments IL-6, IL-8 and TNF expression in A549 cells
Source: Annual Congress 2011 - Lung development and neoplasia
Year: 2011

Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts
Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease
Year: 2008

Phosphodiesterase 4 and 5 inhibitors decrease HO-1 and IL-8 gene expression induced by cigarette smoke
Source: Annual Congress 2008 - Pathophysiology of pulmonary hypertension
Year: 2008


Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells
Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies
Year: 2020