Cigarette smoke alters primary human bronchial epithelial cell (PBEC) differentiation atAir-Liquid Interface (ALI): role of Oct-4, CD146 and CD105.

R. Gagliardo (Palermo, PA, Italy)

Source: International Congress 2017 – Cigarette smoke and particulate matter: basic science and clinical aspects
Session: Cigarette smoke and particulate matter: basic science and clinical aspects
Session type: Poster Discussion
Number: 4447
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Gagliardo (Palermo, PA, Italy). Cigarette smoke alters primary human bronchial epithelial cell (PBEC) differentiation atAir-Liquid Interface (ALI): role of Oct-4, CD146 and CD105.. 4447

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Cigarette smoke alters primary human bronchial epithelial cell (PBEC) differentiation at air-liquid interface (ALI) and induces expression of CD105 and CD146
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016

Cigarette smoke condensate (CSC) increases the expression of beta–defensin-3 (hBD-3) in cultured primary bronchial epithelial cells (PBEC)
Source: Eur Respir J 2005; 26: Suppl. 49, 554s
Year: 2005

Azithromycin differentially affects IL-13 induced periostin (POSTN), CLCA1 and SERPINB2 expression in human bronchial epithelial cells
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015


Cigarette smoke augments MUC5AC mucin production via TLR3-EGFR pathway in airway epithelial cells
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013


The mesenchymal gene, ADAM33, is not expressed during TGFβ-induced epithelial-mesenchymal transition (EMT) in lung epithelial cells
Source: Eur Respir J 2007; 30: Suppl. 51, 60s
Year: 2007

Protective effect of mesenchymal stem cells (MSC) on hypoxia-induced epithelial-mesenchymal transition of alveolar epithelial cells (AEC)
Source: Annual Congress 2012 - Lung injury and repair: reactive oxygen species and beyond
Year: 2012

LSC Abstract – Chronic cigarette smoke (CS) exposure alters differentiation of primary bronchial epithelial cells, cultured at the air-liquid interface (PBEC-ALI)
Source: International Congress 2015 – Cellular and molecular mechanisms of COPD and emphysema
Year: 2015

Parkin-mediated mitophagy is involved in cigarette smoke extract (CSE)-induced cellular senescence in human bronchial epithelial cells (HBEC)
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

TGFβ-induced epithelial to mesenchymal transition (EMT) as a model of COPD
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016

Cigarette smoke decreases E-Cadherin expression downregulating FoxO3 in lung epithelial cells
Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD
Year: 2019

Effect of CCL18 on epithelial-mesenchymal transition (EMT) of alveolar epithelial cells
Source: Annual Congress 2009 - Epithelial cell biology
Year: 2009

Cigarette smoke affects differentiation and function of primary human bronchial epithelial cells
Source: International Congress 2014 – Effect of cigarette smoke on cell behaviour: cell biology, signalling and senescence
Year: 2014

Notch-1 expression is increased by cigarette smoke exposure and its activation up-regulates ki67, PCNA proliferative markers and actin polymerizations in bronchial epithelial cells
Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms
Year: 2019

Cigarette smoke extract, affecting choline acetyltransferase and muscarinic receptor M3 expression, induces MUC5AC in NCI-H292 cell line
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013


Transcriptome analysis of the human airway epithelium during in vitro differentiation
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016

Cigarette smoke upregulating the expression of miR 21 increases IL-8 in airway epithelial cells
Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases
Year: 2018



Cigarette smoke impairs airway epithelial barrier function and cell–cell contact recovery
Source: Eur Respir J 2012; 39: 419-428
Year: 2012



Effect of whole cigarette smoke exposure and CCSP on MUC5AC mucin production in primary cultures of human bronchial epithelial cells at air-liquid interface of COPD, smokers and control patients
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

Differential expression of uPAR in cultured bronchial epithelial cells from asthma patients
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015