The role of STAT3 in T-cell responses during the development of NSCLC

L. Heim (Erlangen, Germany)

Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench
Session: Lung cancer - basic science: the latest results from the bench
Session type: Thematic Poster
Number: 4205
Disease area: Thoracic oncology

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
L. Heim (Erlangen, Germany). The role of STAT3 in T-cell responses during the development of NSCLC. 4205

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The role of NFATc1 in T cell responses during the development of NSCLC
Source: International Congress 2017 – Basic research in lung cancer: a scientific potpourri from genetic alterations to immune cells
Year: 2017


The expression of PD-L1 on the lung cancer cell and its role in T cell anergy
Source: Eur Respir J 2007; 30: Suppl. 51, 289s
Year: 2007

Depletion of STAT6 suppresses lung cancer progression through regulating M2-macrophage polarization
Source: International Congress 2018 – Lung cancer: from the bench to the bedside
Year: 2018

KPNB1-mediated PD-L1 nuclear translocation promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signalling pathway
Source: Virtual Congress 2020 – Biological mechanisms of lung cancer
Year: 2020

The role of CD40 molecule in human lung cancer and its application in immunotherapy
Source: Eur Respir J 2003; 22: Suppl. 45, 199s
Year: 2003

Induced expression of B7-H3 on the lung cancer cells and macrophages suppresses tumor-specific T cell immunity
Source: Annual Congress 2012 - New aspects of lung cancer biology
Year: 2012

c-Met expression induction in immune cells modulates pulmonary fibrosis progression
Source: Virtual Congress 2020 – Physiological and cellular mechanisms affecting pulmonary pathologies
Year: 2020

Specific plasmids encoding shRNA molecules directed against growth factor receptors in cell proliferation inhibition and induction phenotype changes relevant to enhancement of anti-tumor immunity. Model of human non-small (NSCLC) and small (SCLC) cell lung cancer lines
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010

Interleukin-17 enhances the net angiogenic potential and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
Source: Eur Respir J 2004; 24: Suppl. 48, 79s
Year: 2004

EVI5 is an oncogene that regulates the proliferation and metastasis of NSCLC cells
Source: Virtual Congress 2020 – Molecular alterations and immunology in lung cancer
Year: 2020

NTHi-induced inflammation activates the PD-1 immune checkpoint in the tumor microenvironment
Source: International Congress 2018 – Lung cancer: novel molecular markers and mechanisms
Year: 2018



GATA-3 phosphorylation by p38 MAP kinase plays a critical role in regulating Th2 cytokine gene expression
Source: Eur Respir J 2003; 22: Suppl. 45, 386s
Year: 2003

CDCA promotes non-small-cell lung cancer (NSCLC) migration by regulating Akt/Erk1/2 signaling pathways
Source: International Congress 2019 – Thoracic oncology: Treatment, diagnostic options and biology
Year: 2019

NTHi-promoted proliferation of K-ras-induced early lung cancer lesions is fully dependent on Toll-like receptor signaling
Source: International Congress 2017 – Basic research in lung cancer: a scientific potpourri from genetic alterations to immune cells
Year: 2017

Inhibition of osteopontin modulates tumor-stimulated immune response and suppresses mesothelioma progression
Source: Annual Congress 2012 - Biology and treatment of malignant pleural effusions
Year: 2012



P2X7 receptor regulates cell survival, inflammation processes and proliferation of lung carcinoma cells
Source: International Congress 2019 – Novel insights from in vitro and in vivo models of lung disease
Year: 2019

Cytotoxic T cell antigen 4 and the status of T cell activation in lung cancer: local vs. systemic immune response.
Source: International Congress 2017 – Lung cancer: latest basic research on molecular alterations, tumour-immune system-microenvironment interplay and the metabolome
Year: 2017



T-cell susceptibility to glucocorticoid (GC)-induced apoptosis: the role in asthma pathogenesis and therapy
Source: Eur Respir J 2006; 28: Suppl. 50, 227s
Year: 2006

GSK-3 inhibition suppresses lung cancer cell survival, metastasis and proliferation through down-regulation the phosphorylation sites of CAP1
Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench
Year: 2017

CSE exposure abrogates regulatory effects of the bronchial epithelium on B cell survival and IgA production in a coculture system. A pivotal role of TACI
Source: Annual Congress 2012 - Cell culture and animal models of lung disease
Year: 2012