Human airway trypsin-like protease stimulates protease activated receptors and interactions of these receptors Source: International Congress 2019 – Immunopathological mechanisms of lung disease Year: 2019
Eosinophils contribute to extracellular matrix remodeling by enhancing pulmonary fibroblasts proliferation, differentiation and extracellular matrix proteins production in asthma Source: International Congress 2018 – Identification of therapeutic targets for asthma Year: 2018
Soluble biglycan promotes ovalbumin induced airway inflammation by modulating dendritic cell function in mice Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of asthma Year: 2019
Detection and inhibition of ENaC-activating proteases associated with airway dehydration in COPD Source: International Congress 2017 – From the bench: therapeutic approaches in COPD and emphysema Year: 2017
Decreased levels of secretory leucoprotease inhibitor in the pseudomonas -infected cystic fibrosis lung are due to neutrophil elastase degradation Source: Annual Congress 2009 - Airway inflammation and host defence Year: 2009
Lysosomal cysteine proteases in the lung: role in protein processing and immunoregulation Source: Eur Respir J 2004; 23: 620-628 Year: 2004
SerpinB1 in cystic fibrosis airway fluids: quantity, molecular form and mechanism of elastase inhibition Source: Eur Respir J 2011; 37: 1083-1090 Year: 2011
Composition of the cellular matrix, nutrition, and hypoxia modulate the secretion and activation of collagenases and their inhibitors in human lung cells Source: Eur Respir J 2001; 18: Suppl. 33, 244s Year: 2001
MSCS ameliorate elastase induced emphysema by suppressing IL-1b, inducing growth factors and proteinase inhibitors Source: Annual Congress 2009 - From emphysema to fibrosis: mechanisms of cellular remodelling in the diseased lung Year: 2009
Compartmentalized neutrophil recruitment and matrix metalloprotease (MMP)-9 release after airway exposure to endotoxin in humans Source: Eur Respir J 2004; 24: Suppl. 48, 554s Year: 2004
PP216 – Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity Source: ERS Lung Science Conference 2021 Year: 2021
Airway proteins involved in bacterial clearance susceptible to cathepsin G proteolysis Source: Eur Respir J 2010; 35: 410-417 Year: 2010
Alternaria fungal extracts disrupt the barrier function and induce secretion of inflammatory cytokines in airway epithelial cellsSource: Annual Congress 2010 - Epithelial cells: cell biology and role in lung disease Year: 2010
Selective inhibition of RANTES-mediated recruitment combined with elimination of cells into the airway lumen explains resolution of lung eosinophilia by steroids Source: Eur Respir J 2002; 20: Suppl. 38, 169s Year: 2002
N-acetyl cysteine inhibits IL-17-induced IL-8 production from human airway smooth muscle cells - a possible role for anti-oxidant treatment in chronic lung rejection? Source: Eur Respir J 2003; 22: Suppl. 45, 202s Year: 2003
Carbocysteine and N-acetyl cysteine inhibit cigarette smoke mediated acetylation of the PMN chemoattractant peptide PGP Source: Annual Congress 2011 - Immunology and cell biology of asthma and COPD Year: 2011
Decreased levels of elafin in the lungs of patients with acute lung injury as a result of proteolytic cleavage by the proteasome Source: Annual Congress 2012 - Mechanistic studies in airway cell biology Year: 2012
Down-regulation of SLPI by cysteinyl leukotrienes in human bronchial epithelial cells can be reverted by glucocorticoids Source: Annual Congress 2011 - Lung cell injury and repair Year: 2011
Ageing and smoking contribute to plasma surfactant proteins and protease imbalance with correlations to airway obstruction Source: Annual Congress 2011 - The ageing pulmonary interstitium Year: 2011
Thrombin stimulates mucin secretion from airway epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 570s Year: 2002