The mesenchymal factors Neuregulin-1ß and Leptin modulate alveolar epithelial ion transport

M. Laube (Leipzig, Germany)

Source: International Congress 2017 – Molecular biology of normal and abnormal lung development
Session: Molecular biology of normal and abnormal lung development
Session type: Oral Presentation
Number: 3226

Congress or journal article abstractWebcastSlide presentationE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Laube (Leipzig, Germany). The mesenchymal factors Neuregulin-1ß and Leptin modulate alveolar epithelial ion transport. 3226

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Cellular cross-talk in the airway epithelial mesenchymal trophic unit
Source: International Congress 2018 – Cross-talk in the lung microenvironment: implications for chronic lung disease
Year: 2018


Altered pathways from alveolar epithelial cells
Source: ERS Research Seminar 2017 – Integrating systems biology approach in idiopathic pulmonary fibrosis research
Year: 2016

PP233 – Crosstalk between lung fibroblasts and mast cells is modified by alveolar extracellular matrix and influences epithelial migration
Source: ERS Lung Science Conference 2021
Year: 2021

Epithelial fibroblast triggering and interactions in pulmonary fibrosis
Source: Eur Respir Rev 2008; 17: 123-129
Year: 2008



Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating hypoxic signaling
Source: International Congress 2015 – The multiple facets of stem and progenitor cells in lung health and disease
Year: 2015



PPARγ agonists modulate transepithelial anion secretion in human airway epithelial cells
Source: Eur Respir J 2005; 26: Suppl. 49, 483s
Year: 2005

Hypoxia impairs β2 adrenergic signalling and stimulation of alveolar reabsorption in rat alveolar epithelial cells
Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury
Year: 2009


Assessment of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells
Source: Annual Congress 2009 - Airway cell biology
Year: 2009


Conditioned medium from human mesenchymal stem cells restores both amiloride sensitive sodium transport and epithelial permeability to protein across alveolar epithelial cell monolayers in an in vitro model of alveolar injury
Source: Annual Congress 2011 - Barrier functions in sepsis and acute lung injury
Year: 2011


Studying ion transport in cultured epithelial cells
Source: Annual Congress 2007 - WS1 - Educational Workshop: epithelial cell biology: culture methods and functional studies
Year: 2007


Damage to alveolar epithelial ion transport by mycoplasmas
Source: Annual Congress 2004 - Cellular injury and repair in the lung
Year: 2004


Alveolar epithelial stem cells in homeostasis and repair
Source: Eur Respir Monogr 2021; 91: 122-133
Year: 2021


Mechanistic target of rapamycin enhances fibrosis in lung by promoting epithelial mesenchymal transition
Source: International Congress 2019 – Intercellular communication in tissue remodelling of chronic lung diseases
Year: 2019



Oral Presentation: TGF-beta1 regulates the epithelial supportive capacity of mesenchymal stromal cells
Source: Lung Science Conference 2012 - Rebuilding a diseased lung: Repair and regeneration
Year: 2012

Protective roles of paracrine factors of bone marrow mesenchymal stem cells in bleomycin induced lung epithelial cell injury in vitro and pulmonary fibrosis in vivo
Source: Annual Congress 2010 - Experimental approaches in pulmonary fibrosis
Year: 2010


Activation of bone morphogenetic protein(BMP)/Smad signaling in bronchial epithelial cells during airway inflammation
Source: Eur Respir J 2002; 20: Suppl. 38, 372s
Year: 2002

Interleukin-13 regulates the epithelial ion transport in lower airways in vivo
Source: Annual Congress 2010 - Epithelial cells: cell biology and role in lung disease
Year: 2010

Role of the TGFß1-mTOR axis in fibroblast-directed alveolar epithelial regeneration in IPF
Source: International Congress 2019 – Damage and remodelling in pulmonary fibrosis
Year: 2019