Pharmacological validation of a new IPF bleomycin-induced mouse model

F. Stellari (Parma, Pr, Italy)

Source: International Congress 2017 – Towards better treatments for lung disease: experimental pharmacology
Session: Towards better treatments for lung disease: experimental pharmacology
Session type: Thematic Poster
Number: 1053
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
F. Stellari (Parma, Pr, Italy). Pharmacological validation of a new IPF bleomycin-induced mouse model. 1053

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
A longitudinal characterization of lymphangiogenesis in bleomycin-induced pulmonary fibrosis mouse model
Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Year: 2012

Effect of Nintedanib in a rat model of bleomycin-induced lung fibrosis: a transcriptome analysis
Source: Virtual Congress 2021 – Developments in biomarkers and treatment strategies for chronic lung diseases
Year: 2021


The novel oligonucleotide therapeutics PK-7010 for TGF-ß1 ameliorates bleomycin-induced pulmonary fibrosis in mice
Source: Virtual Congress 2020 – Translational aspects of idiopathic pulmonary fibrosis
Year: 2020


PBI-compound, a novel first-in-class anti-fibrotic compound, reduces lung fibrosis in the bleomycin-induced lung fibrosis model: A comparative study with pirfenidone
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013


PBI-compound, a novel first-in-class anti-fibrotic compound, inhibits CTGF and collagen production in murine and human fibroblasts, and reduces lung fibrosis in the bleomycin-induced lung fibrosis model
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013


Late Breaking Abstract - MIF inhibition in a murine model of bleomycin-induced lung fibrosis
Source: International Congress 2018 – Molecular mechanisms and treatment of pulmonary hypertension
Year: 2018



Comparison of in-vivo anti-fibrotic effects of pirfenidone and nintedanib in bleomycin-induced pulmonary fibrosis model
Source: International Congress 2019 – Translational aspects of idiopathic pulmonary fibrosis
Year: 2019

Evolution of biomechanical changes in a murine model of bleomycin-induced lung fibrosis: inflammation versus fibrosis
Source: Eur Respir J 2006; 28: Suppl. 50, 396s
Year: 2006

Time-course analysis of bleomycin-induced lung fibrosis in the rat
Source: International Congress 2018 – Pulmonary fibrosis: from models to patients
Year: 2018

A translational value of pulmonary function tests in a mouse model of bleomycin-induced pulmonary fibrosis: effects of approved therapies Nintedanib and Pirfenidone
Source: International Congress 2019 – Assessment and management of immune-mediated interstitial lung diseases
Year: 2019


Development of an integrative approach to identify key molecular targets involved in bleomycin-induced pulmonary fibrosis in rats.
Source: International Congress 2017 – Lung fibrosis: basic science
Year: 2017


LSC Abstract – A human lung explant model of fibrogenesis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis
Source: International Congress 2016 – Molecular immunology of the lung
Year: 2016

Comparison of expression of napsin A and surfactant protein D in bleomycin-induced pulmonary fibrosis mouse model
Source: Annual Congress 2013 –Diffuse parenchymal lung disease I
Year: 2013

Therapeutic efficacy of a novel LPA1 receptor antagonist, UD-009, in a bleomycin-induced pulmonary fibrosis model
Source: International Congress 2016 – Common mechanisms in lung development and fibrosis
Year: 2016

A humanized animal model of pulmonary fibrosis based on cellular senescence
Source: Virtual Congress 2020 – Cellular involvement in lung injury
Year: 2020




Quantitation of hydroxyproline in a mouse model of bleomycin-induced lung fibrosis: comparison with histological analysis
Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis
Year: 2019

The effect of pravastatin on bleomycin-induced lung injury and fibrosis in mouse
Source: Annual Congress 2010 - Determinants of acute lung injury and fibrosis
Year: 2010

Progress in modelling acute lung injury in a pre-clinical mouse model
Source: Eur Respir J 2012; 39: 1062-1063
Year: 2012


CHIT1 is a novel therapeutic target in idiopathic pulmonary fibrosis (IPF): anti-fibrotic efficacy of OATD-01, a potent and selective chitinase inhibitor in the mouse model of pulmonary fibrosis
Source: International Congress 2018 – Progress in basic and translational research on idiopathic interstitial pneumonias
Year: 2018



Late Breaking Abstract - PRRX1 inhibition decreases fibrosis in the bleomycin-induced lung fibrosis model in mice
Source: International Congress 2018 – Regenerative and anti-fibrotic approaches
Year: 2018