Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts
L. Gallelli, G. Pelaia, G. Cuda, A. Vatrella, D. Fratto, V. Gioffrè, B. D‘Agostino, C. Mastruzzo, M. Maniscalco, M. Sofia, N. Crimi, R. Maselli, F. Rossi, F. S. Costanzo, S. A. Marsico, C. Vancheri (Catanzaro, Naples, Catania, Italy)
Source: Annual Congress 2004 - Lung inflammation and fibrogenesis
Session: Lung inflammation and fibrogenesis
Session type: Poster Discussion
Number: 2796
Disease area: Airway diseases
Rating:
You must login to grade this presentation.
Share or cite this content
Citations should be made in the following way:
L. Gallelli, G. Pelaia, G. Cuda, A. Vatrella, D. Fratto, V. Gioffrè, B. D‘Agostino, C. Mastruzzo, M. Maniscalco, M. Sofia, N. Crimi, R. Maselli, F. Rossi, F. S. Costanzo, S. A. Marsico, C. Vancheri (Catanzaro, Naples, Catania, Italy). Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts. Eur Respir J 2004; 24: Suppl. 48, 2796
You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
Related content which might interest you:
Related content which might interest you:
Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease Year: 2008
Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Effects of MAPK inhibitors on H2 O2 -induced IL-8 production and cell death in primary cultures of human bronchial epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004
In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation Source: Annual Congress 2012 - Diffuse parenchymal lung disease I Year: 2012
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK, ERK1/2) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
Dimethylfumarate reduces growth factor- and cytokine-induced IL-6 release from human lung fibroblasts: role of (NF)-κB Source: Annual Congress 2008 - Airway cell biology and immunology Year: 2008
Transforming growth factor-β inhibition of lung fibroblast proliferation is mediated through prostaglandin E2 , via activation of p38 mitogen-activated protein kinase Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms Year: 2005
Effect of PDE4 inhibitors on MAPK activation and IL-8 production on A549 cells following the induction of oxidative stress Source: Eur Respir J 2005; 26: Suppl. 49, 99s Year: 2005
Vitamin E down-modulates activation of NFκB, secretion of IL-8 and expression of cell adhesion molecules in lung epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 620s Year: 2002
Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Interleukin-8 stimulates human airway epithelial cell proliferation through EGFR transactivation Source: Eur Respir J 2003; 22: Suppl. 45, 561s Year: 2003
CCL5 (RANTES) inhibits TGF-β1-induced collagen production in human bronchial epithelial cells by action of Smad protein Source: Annual Congress 2009 - New results in molecular pathology and functional genomics of non-neoplastic lung diseases Year: 2009
Upregulation of the production of TGF-β and IL-4 and downregulation of IL-6 by apoptotic human bronchial epithelial cells: possible role in regulation of epithelial repair following acute lung injury Source: Eur Respir J 2001; 18: Suppl. 33, 477s Year: 2001
Activation of PAR-2 enhances ICAM-1 expression and IL-8 release in airway epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 571s Year: 2002
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
Increased STIM1 expression induced by cigarette smoking extracts regulates the proliferation and production of inflammatory cytokines in human airway smooth muscle cells Source: Virtual Congress 2020 – Effects of environmental exposures on lung pathology Year: 2020
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
Involvement of protein kinase A (PKA) in the IL-1β induced MCP-1 production in human airway smooth muscle cells Source: Eur Respir J 2001; 18: Suppl. 33, 353s Year: 2001