TLR-4 downregulation in COPD impairs cytokine release from monocytes and Th1-lymphocytes in response to bacterial endotoxin Source: Annual Congress 2009 - What is new in molecular pathology and functional genomics of neoplastic and non-neoplastic lung disease? Year: 2009
Upregulated response to chemokines in oxidative metabolism of eosinophils in asthma and allergic rhinitis Source: Eur Respir J 2003; 21: 925-931 Year: 2003
ILC2 cells from severe allergic and eosinophilic asthma demonstrate increased expression of TSLP receptor (TSLPR) and enhanced proliferative capacity. Source: Virtual Congress 2021 – New insight into the immunology of allergies, asthma and COPD: from mouse to man Year: 2021
Transgenic mice overexpressing IL-18 display increased IL-13 in the airways but no changes of the airway hyperresponsiveness in a murine model of late-phase asthma: evidence for a dual role of IL-18 on mucosal Th1/Th2 responses Source: Eur Respir J 2002; 20: Suppl. 38, 1s Year: 2002
A small-molecule compound targeting CCR5 and CXCR3 prevents airway hyperresponsiveness and inflammation Source: Eur Respir J 2008; 31: 783-789 Year: 2008
Over-expression of SIGIRR attenuates TLR 4,5,9-mediated immune responses in human airway epithelial cells Source: Annual Congress 2009 - Mechanisms of infection: what's new? Year: 2009
Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies Year: 2020
Estrogen protects against airway inflammation via upregulation of SLPI and downregulation of IL-33 Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
Differential gene expression and cytokine production from neutrophils in asthma phenotypes Source: Eur Respir J 2010; 35: 522-531 Year: 2010
Concomitant exposure to nicotine and endotoxin in vitro induces murine airway hyperreactivity possibly via nicotine-induced upregulation of toll-like receptors Source: Annual Congress 2011 - New mechanisms in airway disease Year: 2011
Attenuated cytokine response and enhanced toll-like receptor expression by budesonide in bronchial epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 101s Year: 2006
Protease-activated receptor 1 activation exaggerates allergic airway inflammation in mice Source: Annual Congress 2008 - Understanding allergic airway inflammation with the help of animal models Year: 2008
Interferon-gamma (IFN-γ) alters the expression of IP-10 and IL-18 in human aveolar epithelial cells type II. Possible role in the reinforcement of Th1-dominated lung inflammation Source: Eur Respir J 2001; 18: Suppl. 33, 521s Year: 2001
Interleukin-12 receptor mRNA expression and corticosteroid depended eosinophil apoptosis in asthma Source: Eur Respir J 2003; 22: Suppl. 45, 223s Year: 2003
A dual role of IL-6 signalling and STAT-3 activation on airway inflammation versus airway hyperresponsiveness in a murine model of asthma Source: Eur Respir J 2002; 20: Suppl. 38, 568s Year: 2002
Investigations on the role of region-specific IL-13 receptor alpha 1 expression along the airway tree in mucus production in asthma Source: Annual Congress 2012 - Mechanistic studies in airway cell biology Year: 2012
The expression of IL17RA (the common subunit of IL-17A and IL-25 receptor) on sputum macrophages in asthma patients Source: Virtual Congress 2021 – Pearls in immunology, outcome studies and clinical trials in asthma, alpha-1 antitrypsin deficiency and COPD Year: 2021
Serotonin (5-hydroxytryptamine) modulates cytokine and chemokine production in lipopolysaccharide-primed human monocytes via stimulation of different 5-HT receptor subtypes Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma Year: 2005
CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge Source: Eur Respir J 2004; 23: 876-884 Year: 2004
Increased TGF-β-inducible early gene (TIEG) in human eosinophils stimulated by Th-2 type inflammatory cytokines Source: Eur Respir J 2005; 26: Suppl. 49, 659s Year: 2005