Age-Adjusted D-Dimer Cut Off: Could this prove cost-effective and safe for our Emergency Units?Authors:Mills M, Downey C , Townley S, Kasis A, Dutt T, Gautam M.Introduction:A D-dimer test result (conventionally up to 500 µg/L) is an important component of the diagnostic work-up for patients with suspected VTE, however, it is well known that D-Dimer levels rise with age. Although a negative D-Dimer in conjunction with a clinical probability score can be effective at excluding DVT/PE, studies have proposed that the use of an age-adjusted cut off can increase the number of patients excluded from further testing with a low likelihood of subsequent VTE.This study looked at unselected D-dimer requests from the Emergency department (ED) for patients with suspected DVT/PE to assess the potential impact of introducing age-adjusted D-dimer cut off limits.

A. Kasis (Liverpool, United Kingdom)

Source: International Congress 2017 – Prognostic factors and outcomes in pulmonary embolism

Session: Prognostic factors and outcomes in pulmonary embolism
Session type: Poster Discussion
Number: 554

Disease area: Pulmonary vascular diseases

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A. Kasis (Liverpool, United Kingdom). Age-Adjusted D-Dimer Cut Off: Could this prove cost-effective and safe for our Emergency Units?Authors:Mills M, Downey C , Townley S, Kasis A, Dutt T, Gautam M.Introduction:A D-dimer test result (conventionally up to 500 µg/L) is an important component of the diagnostic work-up for patients with suspected VTE, however, it is well known that D-Dimer levels rise with age. Although a negative D-Dimer in conjunction with a clinical probability score can be effective at excluding DVT/PE, studies have proposed that the use of an age-adjusted cut off can increase the number of patients excluded from further testing with a low likelihood of subsequent VTE.This study looked at unselected D-dimer requests from the Emergency department (ED) for patients with suspected DVT/PE to assess the potential impact of introducing age-adjusted D-dimer cut off limits.. 554

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