The selective CXCR2 receptor antagonist SB-656933 inhibits CXCL1-induced neutrophil CD11b expression in human whole blood Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004
Employing flow cytometric assays of human whole blood neutrophil and monocyte CD11b upregulation and shape change to assess a chemokine receptor (CXCR2) antagonist Source: Annual Congress 2005 - Therapeutic options for COPD: present and future Year: 2005
A CXCR2 antagonist inhibits polyI:C-induced airway neutrophil, but not lymphocyte infiltrate Source: Annual Congress 2011 - Anti-inflammatory strategies in acute lung injury Year: 2011
Inhibition of eosinophil migration by montelukast, a cysteinyl leukotriene receptor antagonist, through down regulation of plasmin activity Source: Eur Respir J 2004; 24: Suppl. 48, 36s Year: 2004
Remifentanil attenuates LPS-induced neutrophil activation Source: Annual Congress 2012 - Infections and sepsis in the ICU Year: 2012
Activation of PAR-2 enhances ICAM-1 expression and IL-8 release in airway epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 571s Year: 2002
Roflumilast potently inhibits CXCL1 mediated neutrophil migration in COPD patients Source: Annual Congress 2011 - COPD: clinical studies and animal cell models Year: 2011
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils Source: Eur Respir J 2003; 22: Suppl. 45, 548s Year: 2003
Effects of CXCR2 antagonists on neutrophil chemotaxis from COPD patients Source: Annual Congress 2010 - Airway cells as targets for anti-inflammatory drugs Year: 2010
Eosinophil adhesion to cholinergic nerve cells induces NFκB activation via the interleukin-1 receptor associated kinase (IRAK) pathway and upregulates ICAM-1 expression Source: Eur Respir J 2003; 22: Suppl. 45, 10s Year: 2003
TNF-α inhibits human eosinophil apoptosis by activating p55 receptor and NF-κB Source: Eur Respir J 2001; 18: Suppl. 33, 162s Year: 2001
Dexamethasone inhibits LPS-induced expression of human β-defensin-2 via down-regulation of TLR4 Source: Eur Respir J 2003; 22: Suppl. 45, 562s Year: 2003
The upregulation of CD-11B expression on circulating neutrophils by CXCL8 and the involvement of CXCR1 in COPD Source: Eur Respir J 2006; 28: Suppl. 50, 749s Year: 2006
LSC 2011 Abstract: P2Y2 receptor regulates VCAM-1 membrane and soluble forms and eosinophil accumulation during lung inflammation Source: Annual Congress 2011 - Experimental modulation of airway inflammation Year: 2011
CXCL-8-dependent and -independent neutrophil activation in COPD: experiences from a pilot study of the CXCR2 antagonist danirixin Source: ERJ Open Res, 6 (4) 00583-2020; 10.1183/23120541.00583-2020 Year: 2020
The pro-apoptotic effect of cysteinyl leukotriene receptor (CysLT-R) antagonist montelukast is mediated by CysLT-Rs expression on antigen-stimulated T cells Source: Eur Respir J 2003; 22: Suppl. 45, 100s Year: 2003
Airway neutrophils have reduced glucocorticoid receptor expression Source: Annual Congress 2008 - Recent advances in the pathogenesis and treatment of asthma and COPD Year: 2008
TLR-4 downregulation in COPD impairs cytokine release from monocytes and Th1-lymphocytes in response to bacterial endotoxin Source: Annual Congress 2009 - What is new in molecular pathology and functional genomics of neoplastic and non-neoplastic lung disease? Year: 2009
Platelet activating factor increases β2 -integrin mediated eosinophil adhesion to ICAM-1 through focal clustering of CD11b Source: Annual Congress 2004 - Genetics and molecular mechanisms of COPD and asthma Year: 2004
Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies Year: 2020