LSC - 2017 - A critical role for mTOR regulated metabolic reprogramming during TGF-ß induced fibroblast collagen synthesis Source: International Congress 2017 – Novel mechanisms and therapeutic targets in lung injury and repair Year: 2017
Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009
In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation Source: Annual Congress 2012 - Diffuse parenchymal lung disease I Year: 2012
Jun kinase regulates the expression of TGF-beta induced connective tissue growth factor in human lung fibroblast Source: Annual Congress 2004 - Inflammation and remodelling in human lungs Year: 2004
Hepatocyte and keratinocyte growth factor (HGF and KGF prevent rat alveolar type II cells from mechanical stretch induced apoptosis – role of phosphoinositide 3-OH kinase Source: Eur Respir J 2007; 30: Suppl. 51, 292s Year: 2007
Roles of Rho-Rock and Smad pathways in TGFβ1-mediated lung fibroblast differentiation Source: Annual Congress 2008 - Regulatory mechanisms of cell activation, renewal and recruitment Year: 2008
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
Inhibition of VEGF blocks TGF-β1 production through a PI3K/Akt signalling pathway Source: Eur Respir J 2008; 31: 523-531 Year: 2008
RB2/p130 gene-enhanced expression downregulates vascular endothelial growth factor expression and inhibits angiogenesis in vivo Source: Eur Respir J 2002; 20: Suppl. 38, 3s Year: 2002
Transforming growth factor-β inhibition of lung fibroblast proliferation is mediated through prostaglandin E2 , via activation of p38 mitogen-activated protein kinase Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms Year: 2005
ERK1/2 mediated expression and release of VEGF in human airway smooth muscle cells in relation to fibroblast growth factors: role of azithromycin Source: Annual Congress 2009 - Airway cell biology Year: 2009
p38 MAPK/MSK1/CREB signal pathway involves in transforming growth factor-β-induced heme oxygenase-1 expression in human lung epithelial cells Source: Eur Respir J 2007; 30: Suppl. 51, 544s Year: 2007
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
VEGF induces ECM synthesis and fibroblast activity in human lung fibroblasts Source: International Congress 2017 – Towards better treatments for lung disease: experimental pharmacology Year: 2017
miR-146a-5p plays an essential role in the aberrant epithelial–fibroblast cross-talk in COPD Source: Eur Respir J, 49 (5) 1602538; 10.1183/13993003.02538-2016 Year: 2017
LSC - 2017 - mTOR-mediated cap-dependent translation is essential for human lung myofibroblast differentiation and collagen I synthesis Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis Year: 2017
BMP-Smad1 target gene Wnt inhibitory factor 1 (WIF1) coordinates BMP and Wnt signaling activities in regulating lung development in vivo Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases Year: 2010
FKBP10 regulates fibroblast migration via synthesis of collagen VI Source: ERS Lung Science Conference 2018 Year: 2018
P38 signalling pathway in primary cultures of human bronchial epithelial cells: effects of transforming growth factor-β and pharmacological modulation by budesonide Source: Eur Respir J 2002; 20: Suppl. 38, 571s Year: 2002