Source: International Congress 2016 – Mechanisms of disease
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
Ruth Saunders (Leicester, United Kingdom), Ruth Saunders, Michael Biddle, Adam Wright, Latifa Chachi, Amanda Sutcliffe, Rachid Berair, Christopher Brightling. DP2/CRTh2 is expressed by ASM cells in asthma and its inhibition suppresses ASM migration. Eur Respir J 2016; 48: Suppl. 60, 4653

Member's Comments

No comment yet.

Related content which might interest you: MNK-1 inhibition reduces proliferation and CXCL10 in airway smooth muscle cells Source: Annual Congress 2013 –Airway smooth muscle and cell biology Year: 2013 Integrins regulate eosinophil adhesion to the airway smooth muscle cells in asthma patients Source: International Congress 2015 – Asthma mechanisms and management Year: 2015 Eosinophil-induced airway smooth muscle cells remodeling is attenuated by blocking of RGD-binding integrins in asthma Source: International Congress 2016 – New findings in mucosal immunology Year: 2016 p53 dysfunction increased mitochondrial biogenesis and bronchial smooth muscle cell proliferation in asthma Source: International Congress 2015 – Airway remodelling: recent developments Year: 2015 CCL2 release by airway smooth muscle is increased in asthma and promotes fibrocyte migration Source: International Congress 2014 – Cell biology 2014 Year: 2014 FGF-2 modulates human airway smooth muscle contractile protein expression and cell stiffness Source: Annual Congress 2013 –Airway smooth muscle and cell biology Year: 2013 Impaired inhibitory action of corticosteroids on chemokine expression induced by TNFalpha in airway smooth muscle (ASM) cells from patients with severe asthma Source: Annual Congress 2013 –Airway smooth muscle and cell biology Year: 2013 TGF-beta alters TRPC6 expression and calcium handling via smad2/3 in human airway smooth muscle Source: Annual Congress 2013 –Airway smooth muscle and cell biology Year: 2013 Airway smooth muscle contractility is increased following coculture with fibrocytes Source: International Congress 2016 – Mechanisms of disease Year: 2016 WNT-5A and WNT-11 as novel regulators of the contractile airway smooth muscle phenotype Source: Annual Congress 2013 –Airway smooth muscle and cell biology Year: 2013 A functional role for WNT-5A in driving airway myocyte proliferation Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation Year: 2013 Targeting ASK1 in preventing airway smooth muscle growth: Implications for airway remodeling in COPD Source: International Congress 2016 – New findings in mucosal immunology Year: 2016 Regulation of actin dynamics by WNT-5A: Implications for human airway smooth muscle contraction Source: International Congress 2016 – Studies in airway cell biology Year: 2016 Link between airway inflammation and remodeling: TNFα induces airway smooth muscle cell proliferation via an ET1/GMCSF/IL6 network Source: International Congress 2015 – Airway remodelling: recent developments Year: 2015 Extracellular matrix within the airway smooth muscle layer correlates with age but not in cases of asthma Source: International Congress 2016 – Translational studies in lung disease Year: 2016 Compound A (CpdA) suppressed production of corticosteroid-resistant chemokines via GR-independent mechanisms in airway smooth muscle (ASM) cells Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases Year: 2013 Effect of oxidative stress on mitochondrial function in airway smooth muscle (ASM) cells from COPD patients Source: Annual Congress 2013 –Airway smooth muscle and cell biology Year: 2013 The c-jun N-terminal kinase signaling pathway regulates airway smooth muscle cell proliferation Source: International Congress 2014 – Cell biology 2014 Year: 2014 HMGB1 is upregulated in ASM in asthma and induces ASM contraction via TLR4 Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects Year: 2015 Upregulation of airway smooth muscle (ASM) cell apoptosis may limit ASM growth during airway remodeling in experimental asthma Source: Annual Congress 2008 - Novel mechanisms in the pathogenesis of pulmonary inflammation Year: 2008