Glucocorticoid-induced transcriptional regulators in human airway cells and airways

Robert Newton (Calgary, AB, Canada), Mahmoud Mostafa, Rider Christopher, Leigh Richard, Robert Newton

Source: International Congress 2016 – Studies in airway cell biology
Session: Studies in airway cell biology
Session type: Thematic Poster
Number: 3988
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Robert Newton (Calgary, AB, Canada), Mahmoud Mostafa, Rider Christopher, Leigh Richard, Robert Newton. Glucocorticoid-induced transcriptional regulators in human airway cells and airways. Eur Respir J 2016; 48: Suppl. 60, 3988

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Anti-inflammatory effects of resveratrol analogues in cellular models of airway inflammation
Source: International Congress 2015 – Advances in the future treatment of COPD
Year: 2015

Anti-inflammatory action of Gibberellin in lung epithelial cells is mediated by modification of NF-κB related kinase expression
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Inhibitors of apoptosis proteins in asthmatic airway inflammation
Source: Annual Congress 2013 –Asthma: new mechanisms and markers
Year: 2013


Enhanced inflammatory gene expression in bronchial epithelial cells from asthmatic patients: Attenuation by a Brd4 mimic
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014


Activation of the β-catenin pathway by Wnt-1 treatment suppress inflammation in the mouse model of allergic airway disease
Source: International Congress 2015 – Advances in asthma and allergy in animal models
Year: 2015


Glucocorticoids and indacaterol regulated gene expressions profiling in human bronchial epithelial cells
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013

The anti-inflammatory effects of sulforaphane are not mediated by the Nrf2 pathway
Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases
Year: 2014

Inhibition of phosphodiesterase 4B enhances glucocorticoid-dependent gene transcription in human airway epithelial cells: Implications for the treatment of COPD
Source: Annual Congress 2013 –New drugs in respiratory medicine
Year: 2013


Azithromycin augments rhinovirus-induced expression of IFNbeta and IFNλ1 in asthmatic bronchial epithelial cells by up-regulating RIG-I like receptors
Source: International Congress 2014 – Novel evidence relating to respiratory treatment development
Year: 2014

Regulation of inflammatory cytokines in human immunocompetent cells by propranolol in vitro
Source: International Congress 2016 – Laboratory tests and cell biology in allergy and immunology
Year: 2016

COPD airway epithelium secretion attracts and activates neutrophils
Source: International Congress 2014 – Novel evidence relating to respiratory treatment development
Year: 2014

Aerobic training reverses airway inflammation by increasing the expression of anti-inflammatory cytokines by peribronchial cells but not by skeletal muscle
Source: International Congress 2015 – Inflammation and remodelling in lung disease
Year: 2015


cPLA2alpha inhibitor ASB14780 suppresses airway MMP-9 production and improves respiratory function in cigarette-smoke induced model
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014


Compound A modulates steroid insensitive chemokines in airway smooth muscle cells via IRF-1 dependent and independent pathways
Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD
Year: 2015

Potential role of SPARC, a downstream mediator of TGF-b in chronic airways disease
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015

Expression of CysLT2 receptors in asthmatic lung, and the roles in bronchoconstriction
Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases
Year: 2014

Vitamin D increases anti-microbial activity in human airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

A role for the WFDC protein, WAP2, in regulation of innate host defence in the lung
Source: International Congress 2014 – New studies into pulmonary proteases and antiproteases
Year: 2014

Impaired inhibitory action of corticosteroids on chemokine expression induced by TNFalpha in airway smooth muscle (ASM) cells from patients with severe asthma
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

Anti-inflammatory effects of the novel phosphodiesterase type 4 inhibitor CHF6001 on COPD alveolar macrophages and lung tissue
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014