LATE-BREAKING ABSTRACT: TRINITY: A phase III study to compare the efficacy and safety of an extrafine triple combination of beclometasone dipropionate (BDP), formoterol fumarate (FF), and glycopyrronium bromide (GB) pMDI (CHF5993) with tiotropium (Tio) and a free triple combination of BDP/FF (Foster®) + Tio in COPD patients

Jørgen Vestbo (Manchester, United Kingdom), Jorgen Vestbo, Massimo Corradi, Isabella Montagna, Géraldine Cohuet, Catherine Francisco, Stefano Vezzoli, Annamaria Muraro, Stefano Petruzzelli, Mario Scuri, Dave Singh

Source: International Congress 2016 – Late-breaking topics in airways disease
Session: Late-breaking topics in airways disease
Session type: Oral Presentation
Number: 1972
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Jørgen Vestbo (Manchester, United Kingdom), Jorgen Vestbo, Massimo Corradi, Isabella Montagna, Géraldine Cohuet, Catherine Francisco, Stefano Vezzoli, Annamaria Muraro, Stefano Petruzzelli, Mario Scuri, Dave Singh. LATE-BREAKING ABSTRACT: TRINITY: A phase III study to compare the efficacy and safety of an extrafine triple combination of beclometasone dipropionate (BDP), formoterol fumarate (FF), and glycopyrronium bromide (GB) pMDI (CHF5993) with tiotropium (Tio) and a free triple combination of BDP/FF (Foster®) + Tio in COPD patients. Eur Respir J 2016; 48: Suppl. 60, 1972

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
LATE-BREAKING ABSTRACT: TRILOGY: a phase III study to evaluate the efficacy and safety of an extrafine triple combination of beclometasone dipropionate (BDP), formoterol fumarate (FF), and glycopyrronium bromide (GB) pMDI (CHF5993) in COPD patients
Source: International Congress 2016 – Pharmacological treatment of COPD: focus on LABA/LAMA combinations
Year: 2016


Sequential flexible therapy with formoterol (Foradil®) plus budesonide (Miflonide®) versus a fixed combination of salmeterol and fluticasone (Seretide®) in asthma self-management
Source: Eur Respir J 2002; 20: Suppl. 38, 388s
Year: 2002

Benefit of FDC budesonide (BUD) and formoterol fumarate (FF) FDC delivered by a novel MDI co-suspension technology (BFF MDI), in patients (pts) with moderate-to-severe COPD
Source: International Congress 2016 – Pharmacological management of COPD
Year: 2016


A comparison of salmeterol xinafoate (SX) plus beclomethasone dipropionate (BDP) and theophylline (Theo) plus BDP in the treatment of moderate chronic obstructive pulmonary disease (COPD)
Source: Eur Respir J 2005; 26: Suppl. 49, 292s
Year: 2005

A comparison of salmeterol xinafoate (SX) plus fluticasone propionate (FP) and slow-release theophylline (Theo) plus FP in the treatment of stable chronic obstructive pulmonary disease (COPD)
Source: Eur Respir J 2006; 28: Suppl. 50, 31s
Year: 2006

Safety and tolerability of the novel inhaled corticosteroid (ICS) fluticasone furoate (FF) in combination with the long-acting beta2 agonist (LABA) vilanterol (VI) administered once daily (OD) in patients with asthma
Source: Annual Congress 2012 - Asthma treatment: efficacy and safety
Year: 2012

Superiority of the ‘triple‘ therapy of salmeterol/fluticasone propionate (SFC) and tiotropium (TIO) vs. individual components in COPD
Source: Annual Congress 2007 - New drugs for COPD
Year: 2007



Onset of action of salmeterol/fluticasone (SFC) in single inhaler vs. salmeterol (S) in patients with COPD
Source: Eur Respir J 2003; 22: Suppl. 45, 285s
Year: 2003

Clinical effects of adding fluticasone propionate/salmeterol (FSC) and tiotropium (TIO) in severe-to-very severe COPD
Source: Annual Congress 2005 - Therapeutic options for COPD: present and future
Year: 2005


Non-inferior efficacy of hydrofluoroalkane (HFA) salmeterol (SALM) metered dose inhaler (MDI) compared to salmeterol chlorofluorocarbon (CFC) in adolescent & adult patients with persistent asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 583s
Year: 2004

Efficacy and safety of the new beclomethasone dipropionate/formoterol combination (HFA MDI) vs. budesonide/formoterol (DPI) in moderate to severe persistent asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 434s
Year: 2006

Single inhaler therapy (SiT) with budesonide/formoterol (BUD/FM) is effective in asthma control
Source: Eur Respir J 2005; 26: Suppl. 49, 124s
Year: 2005

Onset of action of aclidinium (ACL), glycopyrronium (GLY) and tiotropium (TIO): A comparison in COPD patients
Source: International Congress 2015 – New data on established treatments for COPD
Year: 2015

Pharmacokinetic (PK) analysis of fluticasone furoate (FF), umeclidinium (UMEC) and vilanterol (VI) following triple therapy in healthy subjects
Source: International Congress 2014 – Asthma and COPD management
Year: 2014


LATE-BREAKING ABSTRACT: Long-term effects of combined extra-fine beclomethasone (BECL) and formoterol (FORM) treatment in asthma patients
Source: Annual Congress 2009 - Cellular-tissue modifications and functional evaluation in COPD patients
Year: 2009


The combination salmeterol (S) + fluticasone propionate (F) in mild-to-moderate asthma
Source: Eur Respir J 2001; 18: Suppl. 33, 426s
Year: 2001

Relation between the acute response to salbutamol and long-term FEV1 responses to tiotropium (TIO), formoterol (FORM) and its combination (T+F) in COPD patients
Source: Eur Respir J 2003; 22: Suppl. 45, 4s
Year: 2003

LATE-BREAKING ABSTRACT: ENERGITO: Efficacy and safety of once-daily combined tiotropium + olodaterol versus twice-daily combined fluticasone propionate + salmeterol
Source: International Congress 2015 – Emerging strategies for airway disease treatments
Year: 2015


Comparison of fluticasone propionate + salmeterol (FP+S) and montelukast (MK) on bronchial reactivity (BR), pulmonary function (PF) and clinical outcome in children with mild asthma
Source: Annual Congress 2009 - Drug treatment of childhood asthma: the controversies and the issues
Year: 2009


Bronchodilator response of single dose of tiotropium (Tio) plus formoterol (Formo) versus four doses of ipratopium (Ipra) plus salbutamol (Salb) over 24 hours in subjects with moderate-to-severe stable COPD
Source: Annual Congress 2008 - Diagnosing, monitoring and treating respiratory diseases in primary care
Year: 2008