Dipeptidyl peptidase-4 (DPP-4) may predict response to tralokinumab in patients with asthma

Koustubh Ranade (Potomac, United States of America), Koustubh Ranade, Michael Kuziora, Tuyet-Hang Pham, Gautam Damera, Philip Z. Brohawn, Fernanda Pilataxi, Katie Streicher, Scott Martinez, Inna Vainshtein, Meina Liang, Dewei She, Edward Piper, Chrisopher E. Brightling, Richard Martin

Source: International Congress 2016 – Asthma: from basic mechanisms to novel therapeutic perspectives
Session: Asthma: from basic mechanisms to novel therapeutic perspectives
Session type: Oral Presentation
Number: 1796
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Koustubh Ranade (Potomac, United States of America), Koustubh Ranade, Michael Kuziora, Tuyet-Hang Pham, Gautam Damera, Philip Z. Brohawn, Fernanda Pilataxi, Katie Streicher, Scott Martinez, Inna Vainshtein, Meina Liang, Dewei She, Edward Piper, Chrisopher E. Brightling, Richard Martin. Dipeptidyl peptidase-4 (DPP-4) may predict response to tralokinumab in patients with asthma. Eur Respir J 2016; 48: Suppl. 60, 1796

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
LATE-BREAKING ABSTRACT: Lack of association between circulating dipeptidyl peptidase-4 and type 2 biomarkers in asthma; data from U-BIOPRED and BIOAIR cohorts
Source: International Congress 2016 – Laboratory tests and cell biology in allergy and immunology
Year: 2016

Reduction in systemic inflammation by the PDE4 inhibitor roflumilast in patients with COPD
Source: International Congress 2014 – Asthma and COPD devices and treatments
Year: 2014

In vitro profile of the new inhaled pan-JAK inhibitor LAS194046
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

Bronchial asthma (BA) pharmacogenetic profile and therapeutic resistance in slavic population
Source: Annual Congress 2013 –Is it really asthma?
Year: 2013



ADEPT, airway disease endotyping for personalized treatment: Interim analysis of asthma patients
Source: Annual Congress 2013 –Novel drugs and biomarkers in respiratory medicine
Year: 2013

Study of therapeutics effects of montelukast in asthmatic children
Source: International Congress 2016 – Drugs, bugs, BMI, and other problems in paediatric asthma
Year: 2016

Dipeptidyl peptidase I (DPPI) cleaves surfactant protein D (SP-D): A mechanism for immune compromise in the lung
Source: International Congress 2016 – Molecular immunology of the lung
Year: 2016



Safety, tolerability and pharmacokinetics of CHF 6001, a novel selective inhaled PDE4 inhibitor, in healthy volunteers
Source: International Congress 2016 – Preclinical pharmacology: drug targets and mechanisms of action
Year: 2016


In vitro characterization of a novel inhaled PI3Kd inhibitor LAS194223
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

Additive anti-inflammatory effect of glucocorticoids and PDE4 inhibitors on COPD CD8 cells
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

Long-acting anti-muscarinic agents (LAMA) frequency of use and clinical features of patients with severe asthma in real-life setting: data from the Severe Asthma Network in Italy (SANI) registry
Source: International Congress 2019 – Asthma: outcomes of clinical trials and cohorts
Year: 2019


Effect of aclidinium bromide on dyspnoea and health status in patients with stable COPD: Phase III data by GOLD 2013 classification
Source: International Congress 2014 – Asthma and COPD management
Year: 2014

Effect of obesity and metabolic syndrome in patients with bronchial asthma
Source: International Congress 2015 – Clinical assessment in asthma and COPD
Year: 2015


LATE-BREAKING ABSTRACT: Anti-inflammatory effect of a novel inhaled dual PDE3/4 inhibitor RPL554 in man, a unique “first-in-class” drug for the treatment of COPD & asthma
Source: Annual Congress 2013 –Hot topics on airway diseases: new horizons in treatment
Year: 2013

LATE-BREAKING ABSTRACT: Oral corticosteroid-sparing effect of mepolizumab in severe eosinophilic asthma: the SIRIUS study
Source: International Congress 2014 – The future has started: emerging potentials for personalised asthma treatment
Year: 2014

Safety and tolerability of acute dosing of beta-blockers in asthma
Source: Annual Congress 2013 –Asthma and COPD management: novel clinical findings
Year: 2013

Experience of application the selective phosphodiesterase-4 inhibitor roflumilast in the patient with COPD and the metabolic syndrome
Source: International Congress 2016 – Novel avenues in the treatment of COPD II
Year: 2016


Safety of tiotropium in renally impaired patients
Source: International Congress 2014 – Asthma and COPD devices and treatments
Year: 2014


Inflammation in COPD patients before and after roflumilast treatment
Source: International Congress 2014 – Asthma and COPD devices and treatments
Year: 2014

P-PiXel: A ’real-life’ evaluation of omalizumab use in asthmatic patients
Source: International Congress 2016 – Asthma management
Year: 2016