A novel flow cytometric based method to measure kinase inhibition in sputum from COPD subjects

Grant Nicholson (London, United Kingdom), Grant Nicholson, Rebecca Holloway, Brian Leaker, Iain Kilty, Mikhail Salganik, Peter Barnes, Louise Donnelly

Source: International Congress 2016 – What's new in biomarker analysis?
Session: What's new in biomarker analysis?
Session type: Thematic Poster
Number: 914
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Grant Nicholson (London, United Kingdom), Grant Nicholson, Rebecca Holloway, Brian Leaker, Iain Kilty, Mikhail Salganik, Peter Barnes, Louise Donnelly. A novel flow cytometric based method to measure kinase inhibition in sputum from COPD subjects. Eur Respir J 2016; 48: Suppl. 60, 914

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Detection of STAT1 phosphorylation in COPD sputum by flow cytometry
Source: Annual Congress 2013 –COPD: experimental biology
Year: 2013

IL32 expression in induced sputum of COPD subjects
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013


The effect of in vitro culture methods on corticosteroid sensitivity in COPD alveolar macrophages
Source: Annual Congress 2013 –COPD: experimental biology
Year: 2013

Monocyte sub-populations do not reflect differences in COPD macrophage phenotype
Source: International Congress 2015 – Mucosal immunology: what’s new in 2015
Year: 2015

Enhanced neutrophil extracellular trap (NET) formation in sputum of stable COPD patients
Source: International Congress 2015 – Mucosal immunology: what’s new in 2015
Year: 2015


Impaired monocyte chemotaxis in COPD
Source: International Congress 2015 – Mucosal immunology: what’s new in 2015
Year: 2015


Macrophage migration inhibition factor in peripheral blood and induced sputum in patients with COPD
Source: International Congress 2014 – Basic and translational research in asthma and COPD
Year: 2014

Monocyte-derived macrophages from non-smoker COPD subjects exhibit defective bacterial phagocytosis
Source: International Congress 2015 – Mucosal immunology: what’s new in 2015
Year: 2015


COPD monocytes differentiate into pro-inflammatory macrophages regardless of environment
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Increased expression of sphingosine-1-phosphate and S1PR2 are associated with attenuated macrophage phagocytosis in COPD
Source: Annual Congress 2013 –COPD: experimental biology
Year: 2013

Flow cytometric assessment of sputum lymphocyte cytokine profiles in patients with asthma and COPD
Source: Eur Respir J 2001; 18: Suppl. 33, 316s
Year: 2001

Distinct localization of estrogen receptors in lungs of severe COPD patients
Source: International Congress 2015 – New insights into lung disease pathogenesis
Year: 2015

Identification of Ki67+ ’monocytic’ cells within the lungs
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016


Altered P2 receptor expression profile in sputum cells of patients with COPD
Source: International Congress 2014 – Monitoring COPD with different biomarkers
Year: 2014

Elevated GM-CSF in COPD may drive defective macrophage phenotype
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Endothelial microparticles in sputum of COPD patients: A potential biomarker of disease
Source: International Congress 2015 – Systemic and airway biomarkers
Year: 2015

Neutrophil numbers are decreased in bronchial biopsies from patients with COPD
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013

Macrophage phenotype does not affect protease anti-protease imbalance in COPD
Source: International Congress 2015 – New insights into lung disease pathogenesis
Year: 2015

Distribution of blood eosinophil in COPD patients
Source: International Congress 2014 – Lung function, COPD and inflammation
Year: 2014


Increased susceptibility of M2 monocyte-derived macrophages from COPD patients to oxidative stress
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013