A functional variant of secretory leukocyte protease inhibitor (SLPI) with improved anti-inflammatory activity against pulmonary infection Source: Lung Science Conference 2015 Year: 2015
SerpinB1 in cystic fibrosis airway fluids: quantity, molecular form and mechanism of elastase inhibition Source: Eur Respir J 2011; 37: 1083-1090 Year: 2011
Development of secretory leukocyte protease inhibitor (SLPI) variants resistant to degradation by neutrophil elastase Source: International Congress 2014 – New studies into pulmonary proteases and antiproteases Year: 2014
Role of secretory leukocyte protease inhibitor in the development of subclinical emphysema Source: Eur Respir J 2002; 19: 1050-1057 Year: 2002
Alpha-1 antitrypsin genotypes and associated inhibitory activity towards neutrophil serine proteinases, in vitro Source: International Congress 2015 – Promising novel findings in translational pulmonary research Year: 2015
Alpha-1 antitrypsin genotypes and associated inhibitory activity towards neutrophil serine proteinases, in vivo Source: International Congress 2015 – Translational research in respiratory care: new findings Year: 2015
Decreased levels of secretory leucoprotease inhibitor in the pseudomonas -infected cystic fibrosis lung are due to neutrophil elastase degradation Source: Annual Congress 2009 - Airway inflammation and host defence Year: 2009
In vitro and in vivo characterisation of the novel neutrophil elastase inhibitor BI 1323495 Source: Virtual Congress 2020 – Scientific advances in airway pharmacology Year: 2020
Ambroxol suppresses influenza-virus proliferation in the mouse airway by increasing antiviral factor levels Source: Eur Respir J 2002; 19: 952-958 Year: 2002
Increased serum concentration of urinary trypsin inhibitor with asthma exacerbation Source: Eur Respir J 2003; 22: 739-742 Year: 2003
Increased detection of interleukin-;5 in sputum by addition of protease inhibitors Source: Eur Respir J 2001; 18: 685-691 Year: 2001
Effect of proteinase inhibitor from crataeva tapia (cratabl) in distal lung mechanical, inflammatory and remodeling alterations induced by elastase in mice Source: Annual Congress 2011 - Anti-inflammatory strategies in acute lung injury Year: 2011
Lysosomal cysteine proteases in the lung: role in protein processing and immunoregulation Source: Eur Respir J 2004; 23: 620-628 Year: 2004
Secretory leukoprotease inhibitor (SLPI) is removed from media of primary bronchial epithelial cells (PBEC) in the presence of neutrophil elastase (NE) Source: Eur Respir J 2005; 26: Suppl. 49, 554s Year: 2005
Secretory leucoprotease inhibitor (SLPI) inhibits IL-8 expression induced by double-stranded RNA in airway epithelial cells Source: Annual Congress 2008 - Airway cell biology Year: 2008
Macrophage chromatin condition and protease inhibitor activity studying in brush-biopsies at patients with infectious COPD exacerbation Source: Eur Respir J 2007; 30: Suppl. 51, 142s Year: 2007
In vivo pharmacological profile of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-α converting enzyme and matrix metalloproteinases, in models of airway inflammation Source: Eur Respir J 2002; 20: Suppl. 38, 169s Year: 2002
Antithrombin plus alpha–1 protease inhibitor does not affect pulmonary inflammation and coagulation in a ‘double-hit’ lung injury model Source: International Congress 2018 – Preclinical and clinical studies of critical illness Year: 2018
Effect of recombinant α-1 antitrypsin (rAAT) and TAPI on neutrophil elastase (NE) and matrix metalloproteinase-9 (MMP9) activity in induced sputum (IS) from healthy smokers and patients with chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2003 - Progress on therapy for chronic obstructive pulmonary disease Year: 2003
The mechanism of plasminogen activator inhibitor type-1 (PAI-1) Cys mutants inhibitory activity towards lung capillaries endothelial cells (HMVEC-L) Source: Eur Respir J 2005; 26: Suppl. 49, 93s Year: 2005