Effect of retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness

Utako Fujii (Okahama, Japan), Utako Fujii, Arihiko Kanehiro, Hiroki Kakuta, Akihiko Taniguchi, Daisuke Morichika, Genyo Ikeda, Genyo Ikeda, Hikari Nakayama, Koichi Waseda, Etsuko Murakami, Nobuaki Miyahara, Mikio Kataoka, Mitsune Tanimoto

Source: International Congress 2015 – Immune aspects of asthma and other airway diseases
Session: Immune aspects of asthma and other airway diseases
Session type: Thematic Poster Session
Number: 4007
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Utako Fujii (Okahama, Japan), Utako Fujii, Arihiko Kanehiro, Hiroki Kakuta, Akihiko Taniguchi, Daisuke Morichika, Genyo Ikeda, Genyo Ikeda, Hikari Nakayama, Koichi Waseda, Etsuko Murakami, Nobuaki Miyahara, Mikio Kataoka, Mitsune Tanimoto. Effect of retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness. Eur Respir J 2015; 46: Suppl. 59, 4007

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Alpha-7 nicotinic receptor stimulation reduces airway inflammation in a murine model of asthma
Source: International Congress 2016 – Airway pharmacology: drug targets and mode of action
Year: 2016

The muscarinic M3 receptor regulates allergen-induced airway remodeling in mice
Source: Annual Congress 2013 –Asthma drugs: new findings
Year: 2013


A novel inhaled PI3Kδ inhibitor, LAS194223 reduces allergen-induced airway inflammation in rat
Source: International Congress 2014 – New drugs for asthma, COPD and pulmonary fibrosis
Year: 2014

An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in the mouse
Source: Annual Congress 2013 –Novel drugs for the treatment of asthma and COPD
Year: 2013

Andrographolide restores steroid sensitivity to block LPS/IFN-γ-induced IL-27 and airway hyperresponsiveness in mice
Source: International Congress 2015 – New models for treating airway diseases
Year: 2015


Activation of the β-catenin pathway by Wnt-1 treatment suppress inflammation in the mouse model of allergic airway disease
Source: International Congress 2015 – Advances in asthma and allergy in animal models
Year: 2015


Treatment with Syk inhibitors after establishment of disease phenotype in a chronic HDM model of allergic airways inflammation abolishes AHR and attenuates inflammatory mediator expression
Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD
Year: 2015

Acid sphingomyelinase deficiency improves lung function in allergen-induced asthma in mice
Source: Annual Congress 2013 –Cell biology and murine models of asthma and inflammation
Year: 2013

Influence of beta2-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients
Source: Annual Congress 2013 –Genetics and genomics of lung disease
Year: 2013

Aerobic training reverses the inhibition in the expression of glucocorticoid receptors and decreases the Th2 allergic inflammation in asthma model
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013


Nicotine impairs inflammation-induced airway relaxation in a in vitro murine model of asthma
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013


LATE-BREAKING ABSTRACT: A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimers
Source: International Congress 2015 – Hot topics on airway diseases: new horizons in treatment
Year: 2015

The effect of lipopolysaccharide-contaminated ovalbumin on airway inflammation and remodeling in a chronic murine asthma model
Source: Annual Congress 2013 –Murine models of lung immunology
Year: 2013


Bcl-2 antagonist ABT-737 attenuates corticosteroid-insensitive neutrophilic airway inflammation
Source: International Congress 2015 – Therapeutic approaches in inflammatory lung disease
Year: 2015


Low level laser in monotherapy or in combination with leukotriene receptor antagonists in the treatment of allergic lung inflammation
Source: International Congress 2015 – Chronic airway disorders: miscellaneous aspects
Year: 2015

Combined loss of M2 and M3 muscarinic acetylcholine receptor (mAChR) function in mutant mice increases serotonin airway responsiveness (AR)
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014

Repeated lipopolysaccharide stimulation causes corticosteroid insensitive inflammation in lung via phosphoinositide-3-kinase δ signaling
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

IL-13 in a mouse model of chemical-induced airway hyperresponsiveness
Source: International Congress 2015 – Immune mechanisms in the human lung
Year: 2015

Lipopolysacharide modulates glucocorticoid receptor function in nasal mucosa and polyp fibroblasts
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013

Transient receptor potential channels in a mouse model of isocyanate-induced airway hyperresponsiveness
Source: International Congress 2014 – Mechanistic murine studies of asthma and lung inflammation
Year: 2014