Inhalation of chlorine causes lung inflammation and airway hyperresponsiveness in a rat model of chemical-induced lung injury

Sofia Jonasson (Umeå, Sweden), Elisabeth Wigenstam, Linda Elfsmark, Bo Koch, Sofia Jonasson

Source: International Congress 2015 – Inflammation and remodelling in lung disease
Session: Inflammation and remodelling in lung disease
Session type: Thematic Poster Session
Number: 3917
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Sofia Jonasson (Umeå, Sweden), Elisabeth Wigenstam, Linda Elfsmark, Bo Koch, Sofia Jonasson. Inhalation of chlorine causes lung inflammation and airway hyperresponsiveness in a rat model of chemical-induced lung injury. Eur Respir J 2015; 46: Suppl. 59, 3917

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Glucagon inhibits airway hyperreactivity and lung inflammation in a murine model of acute lung injury
Source: International Congress 2015 – Therapeutic approaches in inflammatory lung disease
Year: 2015

Targeting the hedgehog/GLI pathway decreases bleomycin-induced lung fibrosis
Source: Annual Congress 2013 –Translational studies in chronic repair and remodelling in the lung
Year: 2013

Tiotropium effects on airway inflammatory events in the cat as an animal model for acute cigarette smoke-induced lung inflammation
Source: International Congress 2014 – Animal models: asthma, COPD and beyond
Year: 2014

Oxidative stress and lung permeability during chlorine-induced acute lung injury in mice
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013


Changes in airway and lung tissue mechanics in aspiration-induced lung injury: Differentiation of direct and indirect mechanisms in a porcine model
Source: Annual Congress 2013 –Various issues in clinical respiratory physiology
Year: 2013


Comparison of pulmonary versus extrapulmonary models of induced acute lung injury in rat
Source: Annual Congress 2013 –Experimental models in critical care
Year: 2013


Effects of N-acetylcysteine on airway inflammation, airway hyperresponsiveness and abnormal lung function in chronic ozone-induced COPD model
Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD
Year: 2012

Exosomal messenger RNAs in the airway are potential biomarkers for acute lung injury in mice
Source: International Congress 2015 – Systemic and airway biomarkers
Year: 2015

Changes of inflammatory markers in the ventilator-induced lung injury model of rabbits
Source: Eur Respir J 2004; 24: Suppl. 48, 265s
Year: 2004

Inhaled silver nanoparticles induce pulmonary oxidative injury and inflammation: Differential effects between rat strains
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014

Chronic intermittent hypoxia exacerbates lung fibrosis in bleomycin-induced lung injury mouse model
Source: International Congress 2018 – Sleep-disordered breathing: cardiovascular consequences, epidemiology, phenotypes and comorbidities
Year: 2018



Strain-specific susceptibility towards ventilator-induced lung injury in infant rats
Source: International Congress 2015 – Neonatal and paediatric intensive care
Year: 2015

Lung parenchyma remodelling in murine model of asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 484s
Year: 2003

The effects of diesel exhausted particles on the oxidative systems in smoking-induced emphysema model
Source: Annual Congress 2013 –Indoor and outdoor pollutants: ventilation, sprays, diesel particles, asthma and COPD
Year: 2013


Stem cell therapy attenuates airway and lung parenchyma remodeling in a murine model of chronic allergic asthma
Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of asthma
Year: 2008


Short-term effects of surfactant administration on regional lung function in a model of ventilator-induced lung injury (VILI) in rabbit
Source: International Congress 2014 – Respiratory pathophysiology: mechanisms of alteration of lung, respiratory and peripheral muscle function
Year: 2014

Novel experimental model of maintained acute lung injury
Source: Annual Congress 2013 –Experimental models in critical care
Year: 2013


Mechanisms responsible for surfactant changes in sepsis-induced lung injury
Source: Eur Respir J 2005; 26: 1074-1079
Year: 2005



Thymosin beta4 protects mice from bleomycin-induced damage in the lung
Source: Annual Congress 2013 –Idiopathic pulmonary fibrosis: clinical view
Year: 2013

Acute protective effect of estradiol on lung inflammation induced by an intestinal ischemic insult in male rats
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013