SIRT1 contributes to LPS-induced lung injury through interaction with mitochondrial ROS generation

Yong Chul Lee (Jeonju, Republic of Korea), Yong Chul Lee, So Ri Kim, Hee Jung Kim, Soon Ha Kim

Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Session: Novel insights into the pathobiology of acute lung injury
Session type: Poster Discussion
Number: 3033
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Yong Chul Lee (Jeonju, Republic of Korea), Yong Chul Lee, So Ri Kim, Hee Jung Kim, Soon Ha Kim. SIRT1 contributes to LPS-induced lung injury through interaction with mitochondrial ROS generation. Eur Respir J 2015; 46: Suppl. 59, 3033

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Activation of NLRP3 inflammasome is regulated by mitochondrial ROS via PI3K-HIF-VEGF pathway in acute lung injury
Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Year: 2015


Chrysin reduces the degree of lung injure which induced by lipopolysaccharides (LPS): Possible involvement of oxidative stress and the NF-κB pathway
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014


Hypoxia induces inflammasome activation and influx of neutrophils and T-cells in the lungs
Source: Annual Congress 2013 –Novel mechanisms in lung injury
Year: 2013


Silica-induced inflammasome activation in vitro and in rat lungs
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013

Plant Kunitz proteinase inhibitor attenuates inflammation, oxidative stress and remodeling induced by elastase in mice
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Targeting the hedgehog/GLI pathway decreases bleomycin-induced lung fibrosis
Source: Annual Congress 2013 –Translational studies in chronic repair and remodelling in the lung
Year: 2013

The roles of inducible NO synthase and reactive oxygen species on lung injury induced by renal ischemia/reperfusion injury in the isolated perfused rat lung
Source: International Congress 2015 – Acute critical care: novelties in critical care
Year: 2015


Inflammation induced conformational changes in Z alpha-1 antirypsin promotes lung Z-AT cell damage
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013

The role of CD74 in experimental and clinical acute lung injury
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014

Cigarette smoke impairs basal cell mediated epithelial wound repair and induces expression of the antimicrobial protein RNase 7 via oxidative stress
Source: International Congress 2015 – Cellular and molecular mechanisms of COPD and emphysema
Year: 2015

Kallistatin protects against LPS-induced mouse lung injury
Source: Annual Congress 2012 - The many roads to lung injury
Year: 2012


The role of pre-receptor glucocorticoid metabolism in regulating the severity and persistence of murine lung injury
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013


Lung expression levels and subcellular localization of heme oxygenase-1 (HO-1) modulate recovery from hyperoxia in neonatal mice
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013


iNOS inhibition modulates lung tissue inflammation via oxidative stress pathway activation
Source: Annual Congress 2008 - Inflammatory trigger mechanisms in asthma and COPD
Year: 2008


Dexamethasone inhibits secretory and cytosolic phospholipases A2 in alveolar macrophages in acute lung injury
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Physical stress modulates distal lung tissue mechanics, inflammation and remodelling associated to iNOS and oxidative stress activation
Source: Annual Congress 2008 - Pathophysiology of respiratory diseases
Year: 2008


Effects of autophagy on LPS-induced lung inflammation and acute lung injury (ALI) in vitro and in vivo
Source: International Congress 2018 – Role of microbial exposure and inflammation in lung injury
Year: 2018

Arginase 1 contributes to fibrogenesis in the lungs of silica-challenge mice
Source: International Congress 2015 – Pulmonary fibrosis: mechanisms of disease
Year: 2015


Ceramide-1-phosphate attenuates cigarette smoke induce lung inflammation
Source: Annual Congress 2013 –Cell biology and murine models of asthma and inflammation
Year: 2013


Role of eNOS in ischemia/reperfusion-induced lung injury
Source: Eur Respir J 2007; 30: Suppl. 51, 293s
Year: 2007