Microvesicles derived from alveolar macrophages mediate epithelial activation via a TNF dependant mechanism

Sanooj Soni (London, United Kingdom), Sanooj Soni, Mariko Yoshida, Samantha Woods, Kieran O’Dea, Michael Wilson, Masao Takata

Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Session: Novel insights into the pathobiology of acute lung injury
Session type: Poster Discussion
Number: 3024

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Sanooj Soni (London, United Kingdom), Sanooj Soni, Mariko Yoshida, Samantha Woods, Kieran O’Dea, Michael Wilson, Masao Takata. Microvesicles derived from alveolar macrophages mediate epithelial activation via a TNF dependant mechanism. Eur Respir J 2015; 46: Suppl. 59, 3024

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
ATP selectively packages TNF within microvesicles released from alveolar macrophages
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016

Heparin effect in alveolar cells and macrophages in an acute lung injury model
Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Year: 2015

Effects of ceramide pathway inhibition on the inflammatory response in lipopolysacharide-triggered lung injury
Source: International Congress 2015 – Respiratory muscles and airways function: from physiology to clinical implications
Year: 2015

LATE-BREAKING ABSTRACT: Activation of MTOR in pulmonary epithelium promotes LPS-induced acute lung injury
Source: International Congress 2016 – Novel mechanisms and therapeutic targets in acute and chronic inflammatory disease
Year: 2016



TNF and IP-10 drive inflammation into hyperinflammation in the murine lung
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013

Characterization of ceramide generation kinetics in a lung injury model induced by lipopolysaccharide
Source: International Congress 2015 – Respiratory muscles and airways function: from physiology to clinical implications
Year: 2015

Down-regulation of RIP140 can prevent LPS-induced inflammation and acute lung injury in mice via PPARγ
Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Year: 2015

The role of SIRT1 in LPS-induced lung endothelial barrier dysfunction and lung injury in vivo
Source: International Congress 2016 – Molecular targets in pulmonary disease
Year: 2016


New IL-1 family IL-38 is highly expressed in alveolar cells of drug-induced lung injury and idiopathic pulmonary fibrosis
Source: International Congress 2016 – ILD pathogenesis
Year: 2016

A mouse model of acute lung injury implicates phospholipase Cε in neutrophilic inflammation through CXC chemokine production
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016


Obesity modulates the alveolar macrophage response
Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Year: 2015

Ventilation-induced neutrophil infiltration depends on nuclear factor-kB and NF-kB repressing factor
Source: Annual Congress 2013 –Novel mechanisms in lung injury
Year: 2013

Heparin effect in pulmonary cell populations in an in-vitro model of acute lung injury
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016


Human mesenchymal stem cells (MSC) modulate alveolar macrophage polarization in vivo and in vitro.
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014

Essential oils reduced lung inflammation in a model of acute lung injury
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014

Src regulates ventilation-induced epithelial-mesenchymal transition and epithelial apoptosis
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014


Proton-sensing TDAG8 exhibits the protective role in lipopolysaccharide-induced acute lung injury
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016


Mesenchymal stem cell-conditioned medium induces neutrophils apoptosis via inhibition of NF-kB pathway and increases endogenous pulmonary stem cells in endotoxin-induced acute lung injury
Source: International Congress 2015 – The multiple facets of stem and progenitor cells in lung health and disease
Year: 2015

LATE-BREAKING ABSTRACT: Human mesenchymal stem cell exosomes attenuates sepsis-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-?B pathway
Source: International Congress 2015 – Acute critical care: mechanical ventilation: how to limit the damage
Year: 2015


Effects of S-nitroso-N-acetyl-penicillamine (SNAP) on inflammation, apoptosis and iNOS activity in an experimental model of acute lung injury
Source: International Congress 2015 – Acute critical care: novelties in critical care
Year: 2015